Results 181 to 190 of about 1,003,844 (306)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Large-scale interspecific associations and ecological context shape communal roosts of Western jackdaw (Coloeus monedula). [PDF]

PLoS One
Palacios-Martínez I, Carrete M, García J, Alonso H, Arizaga J, Frías Ó, Godinho C, Hernández-Brito D, Hortas F, Martín-Zúñiga J, Montoya-Ayala R, Mouriño J, Muñoz AR, Pérez-García JM, Prieta J, Sanz J, Solé-Bujalance L, Travassos P, Villanúa D, Zamora-Marin JM, Blanco G.   +20 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Correction: Liu et al. Analysis of Gut Microbial Communities and Functions in <i>Passer ammodendri</i> Under Two Extreme Environments. <i>Microorganisms</i> 2025, <i>13</i>, 2642. [PDF]

Microorganisms
Liu Y, He P, Liu D, Song Y, Jia C, Wang D, Jin Q, Song G, Wei Q.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Changes in DOM Quality Determine Prokaryotic Activities and Extracellular Release in the NW Mediterranean Sea: An Experimental Approach. [PDF]

Environ Microbiol Rep
Ortega-Retuerta E, Bouchachi N, Campos R, Crispi O, Marie B, Paulin CH, Escoubeyrou K, Colombet J, Sime-Ngando T, Von Jackowski A.   +9 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Antimicrobial resistance varies with warming in active layer soil and permafrost. [PDF]

Sci Rep
Faber Q, Baker CCM, West JR, Doherty SJ, Ernakovich JG, Barbato RA.   +5 more
europepmc   +1 more source

The abundances of constituents of Titan's atmosphere from the GCMS instrument on the Huygens probe

Nature, 2005
H. Niemann, S. Atreya, S. Bauer, G. Carignan, J. Demick, R. Frost, D. Gautier, J. Haberman, D. Harpold, D. Hunten, G. Israel, J. Lunine, W. Kasprzak, T. Owen, Michael B. Paulkovich, F. Raulin, E. Raaen, S. Way   +17 more
semanticscholar   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source