Results 31 to 40 of about 204,301 (258)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Stellar Populations of the Galactic Disk: Metallicity Distribution and Kinematics

open access: yesOpen Astronomy, 2003
Metallicities and distances have been determined from Vilnius photometry for an in situ sample of nearly 650 stars in eight proper-motion fields at high Galactic latitudes.
Bartašiūtė S.   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Observational signatures and constraints on the intermediate neutron-capture process

open access: yesAstronomy & Astrophysics
Context. Observational abundances of carbon enhanced metal-Poor (CEMP) stars with patterns in between those produced by the rapid (r) and slow (s) nucleosynthesis processes (CEMP-rs stars) are currently invoked as evidence of synthesis via the ...
Giribaldi R. E.   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

The Ba Isotopic Ratio as a Way of Distinguishing the R- and S-Process in Chemical Evolution Models

open access: yesGalaxies
Only recently, observational studies have started providing measurements for the barium isotopic ratio in metal-poor stars with unprecedented detail. This new approach can be extremely useful in tracing back the origin of neutron-capture elements, since ...
Federico Rizzuti   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Close Binaries and the Abundance Discrepancy Problem in Planetary Nebulae

open access: yesGalaxies, 2018
Motivated by the recent establishment of a connection between central star binarity and extreme abundance discrepancies in planetary nebulae, we have carried out a spectroscopic survey targeting planetary nebula with binary central stars and previously ...
R. Wesson   +4 more
doaj   +1 more source

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