Results 171 to 180 of about 1,169,779 (313)

Mortise‐Tenon Joint Inspired Weakly Solvated Gel Electrolyte Based on Halogen Bonds for High‐Voltage Lithium Metal Batteries

open access: yesAdvanced Science, EarlyView.
Inspired by “mortise‐tenon joints”, a halogen bond‐mediated solvation regulation strategy is proposed for gel polymer electrolytes. This approach utilizes π‐hole framework directed halogen bond interactions to weaken solvent‐Li+ coordination, thereby inducing an anion‐dominated weakly solvating structure that facilitates the formation of a highly ion ...
Shuohan Liu   +6 more
wiley   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

open access: yesAdvanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye   +18 more
wiley   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

open access: yesAdvanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao   +14 more
wiley   +1 more source

Trends in opioid analgesic abuse and mortality in the United States.

open access: yesNew England Journal of Medicine, 2015
Richard C. Dart   +6 more
semanticscholar   +1 more source

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

open access: yesAdvanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang   +6 more
wiley   +1 more source

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