Results 151 to 160 of about 184,463 (305)

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

Advanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen, Yao Zhao, Yangye Lian, Yifei Hou, Lifen Gong, Tingting Wu, Yulin Yang, Jiaqi Zhu, Xin Wang, Kaihua Zhang, Jing Ding   +10 more
wiley   +1 more source

The Association Between Childhood Trauma and Prodromal Psychotic Symptoms in Nursing Undergraduates: Mediating Roles of Depression and Anxiety. [PDF]

J Multidiscip Healthc
Wang Y, Cai Q, Xu X, Gu J.
europepmc   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Chronic biliary colic associated with ketamine abuse

, 2016
Ahmed Al-Nowfal, Yahya A Al-Abed Department of Surgery, Southend University Hospital, Prittlewell Chase, Westcliff-on-Sea, Essex, UK Introduction: Biliary colic is a common clinical presentation, with the majority of cases being related to gallstone ...
Al-Abed YA, Al-Nowfal A
core  

Advancing health equity for Roma people in Romania. [PDF]

PLOS Glob Public Health
Matache M, Richardson E.
europepmc   +1 more source

Prohibition of abuse of rights

This Article corresponds to Article 30 of the UDHR of 1948, Article 17 of the 1950 ECHR, Article 5 of the 1966 ICCPR, Article 5 of the 1966 ICESCR and Article 29 of the ACHR of 1969.
Caramelo-Gomes, José, Bessa-Vilela, Noémia   +1 more
openaire   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Decreased thickness of the individually-mapped genital cortex after childhood sexual abuse exposure in adult women. [PDF]

Commun Biol
Kovalchuk Y, Schienbein S, Knop AJJ, Bauer M, Spengler S, Brecht M, Haynes JD, Heim C.   +7 more
europepmc   +1 more source

Intrinsic Mechanical Parameters and their Characterization in Solid‐State Lithium Batteries

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
This review focuses on the intrinsic mechanical parameters and their associated characterization in solid‐state batteries. The physical significance of mechanics parameters is introduced with exhaustive classifications by elastic, plastic deformations and fracture in bulk, adhesion, friction at interfaces, and mechanical fatigue in cells ...
Shuai Hao, Qianyi Zhang, Xiangkang Kong, Zhaoxiang Wang, Xue‐Ping Gao, Paul R. Shearing   +5 more
wiley   +1 more source

Aberrant cortico-striato-limbic functional connectivity to alcohol cues in co-occurring bipolar disorder and alcohol use disorder. [PDF]

Neuropsychopharmacology
Mellick WH, Tolliver BK, Anton RF, Prisciandaro JJ.   +3 more
europepmc   +1 more source