Results 121 to 130 of about 105,361 (309)
Advanced Science, EarlyView.The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Advanced Science, EarlyView.Neuroinflammation alters blood–brain barrier integrity and contributes to neurological disorders, yet existing models lack human immune complexity. This study presents a 3D, immune‐responsive platform that reconstructs key neurovascular components and enables real‐time monitoring.
Pavlo Gordiichuk +9 more
wiley +1 more source
Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation
Advanced Science, EarlyView.Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang +6 more
wiley +1 more source
Advanced Science, EarlyView.CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu +12 more
wiley +1 more source
Internal fight : Palestinian abuses in Gaza and the West Bank / Human Rights Watch
, 2008 "This report documents serious human rights abuses over the past year by the competing Palestinian authorities in Gaza and the West Bank, run by Hamas and Fatah, respectively.
unknown
core +1 more source
DISREGARD OF THE CORPORATE ENTITY IN RUSSIAN CASE LAW
International Journal of Law in Changing WorldThis paper reviews the legal doctrines developed in case law and used to challenge corporate decisions and resulting transactions: the doctrine of piercing the corporate veil, the beneficial ownership doctrine, affiliation, and corporate estoppel.
Irina Ivanovna Baukina
doaj +1 more source
Advanced Science, EarlyView.We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Seeing the state: Human rights violations of victims of crime and abuse of power
, 2017 There is a deeply held view within criminology that victims’ rights ‘movements’ are to be resisted. There is equally entrenched opinion amongst victim advocates that persons accused of offences have rights including human rights but persons as victims do
Holder, Robyn
core +1 more source
Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies
Advanced Science, EarlyView.In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang +4 more
wiley +1 more source