Results 51 to 60 of about 330,391 (267)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

A distinct method to eliminate the induced voltage in AC loss determination without phase control

open access: yesAIP Advances, 2020
AC loss is often considered one of the most important design parameters that guide the fabrication of superconducting devices. Thus, the electrometric method to determine AC loss of superconductors is crucial.
Liuyang Shen   +3 more
doaj   +1 more source

A Comprehensive Loss Model and Comparison of AC and DC Boost Converters

open access: yesEnergies, 2021
DC microgrids have become a prevalent topic in research in part due to the expected superior efficiency of DC/DC converters compared to their AC/DC counterparts.
Daniel L. Gerber   +6 more
doaj   +1 more source

Current distribution and AC losses in twisted multifilamentary AC superconductors [PDF]

open access: yesIEEE Transactions on Magnetics, 1989
The development of AC superconductors has led to multifilamentary wires having a highly resistive matrix material and a small twist pitch and filament diameter. A numerical one-dimensional model is presented which enables the authors to calculate the current distribution as well as the magnetization and transport current loss in a current-carrying AC ...
Roovers, A.J.M., van de Klundert, L.J.M.
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers. [PDF]

open access: yesPLoS ONE, 2014
HIV replication is only partially controlled by HIV-specific activated effector T cells in chronic HIV infection and strategies are warranted to improve their efficacy.
Andreas Lind   +5 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Design and Control of Advanced Uninterruptible Power Supplies With SiC MOSFETs for Enhanced Performance and Efficiency

open access: yesIEEE Access
This paper proposes a high-performance high-efficiency single-phase uninterruptible power supply (UPS), which uses totem pole power factor correction in AC/DC stage and three-level T-type inverter in DC/AC stage.
Quoc Nam Trinh, Thanh Hai Nguyen
doaj   +1 more source

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