Results 41 to 50 of about 997,756 (304)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Comparative Analysis and Optimisation Design of Flux Reversal Permanent Magnet Machines for In‐Wheel Applications

open access: yesIET Electric Power Applications
High torque output capability is crucial for electric vehicle in‐wheel machines. In order to comprehensively evaluate the performance of different out rotor flux reversal permanent magnet (FRPM) machines, a comparative study of two FRPM machines with ...
Yunpeng Zhang, Zhenyang Qiao, Weinong Fu
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Extending Service Beyond Active Duty: Generalizability of Rheumatoid Arthritis Research Conducted Among U.S. Veterans

open access: yesArthritis Care &Research, Accepted Article.
Biomedical research involving United States Veterans continues to advance healthcare beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where Veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both ...
Austin M. Wheeler   +20 more
wiley   +1 more source

Numerical Investigation of High-Temperature Superconducting-Coated-Conductors Subjected to Rotating Magnetic Fields

open access: yesSolids, 2022
Over time, high-temperature superconductor (HTS)-coated conductors (CCs) have proven to be promising candidates for future high-efficiency and high-power density electrical machines.
Wafa Ali Soomro   +5 more
doaj   +1 more source

OntOMat: Toward Ontology‐Based Product and Process Design Engineering and Optimization Solutions Fueling Circular Value Chains

open access: yesAdvanced Engineering Materials, EarlyView.
The OntOMat ontology establishes a structured framework for polymer matrix fiber reinforced composite materials, integrating manufacturing processes, characterization methods, and multiscale design through the VDI/VDE 3682 formalized process description standard.
Nicolas Christ   +19 more
wiley   +1 more source

Numerical Study of Multi‐Pole Generator With HTS Windings for Direct Drive Wind Turbines

open access: yesIET Electric Power Applications
High‐temperature superconducting (HTS) materials show potential advantages for direct drive wind turbine generators by enabling higher power density and lower volume. However, incorporating HTS windings necessitates a cryogenic system, which can increase
Shuangrong You   +5 more
doaj   +1 more source

Intelligent Identification Method for ZDJ-9 AC Turnout Switch Machine Faults

open access: yesChengshi guidao jiaotong yanjiu
Objective By analyzing abnormal three-phase action currents of AC switch machines, it is possible to identify faults in the turnout equipment. However, due to the constant operation of switch machines for large number of turnouts on urban rail transit ...
Junjie LIU
doaj   +1 more source

Control Strategies for Open-End Winding Drives Operating in the Flux-Weakening Region [PDF]

open access: yes, 2013
This paper presents and compares control strategies for three-phase open-end winding drives operating in the flux-weakening region. A six-leg inverter with a single dc-link is associated with the machine in order to use a single energy source.
KESTELYN, Xavier   +4 more
core   +1 more source

Fabrication Routes for Ionic Conducting Fiber Strain Sensors

open access: yesAdvanced Engineering Materials, EarlyView.
Ionic conducting fiber strain sensors (ICFSs) offer compliant, textile‐integrable sensing. Thus far, the commercialization of ICFSs has been constrained by fiber fabrication routes. This review provides a fabrication‐centric analysis of ICFSs correlating processing strategies with material properties and scalability.
Leo John Kershaw   +3 more
wiley   +1 more source

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