Results 31 to 40 of about 76,140 (267)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Determination of the Asynchronous Traction Motor Characteristics of Locomotive

open access: yesAdvances in Electrical and Electronic Engineering, 2017
The article deals with the problem of the locomotive asynchronous traction motor control with the AC diesel-electric transmission. The limitations of the torque of the traction motor when powered by the inverter are determined.
Pavel Grigorievich Kolpakhchyan   +5 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Impaired driving due to alcohol or drugs: International differences and determinants based on E-Survey of Road Users' Attitudes first-wave results in 32 countries

open access: yesIATSS Research, 2020
Introduction: Driving while intoxicated is a major risk factor for road traffic crashes, and it is important to understand the global developments, differences between countries, and determinants of driving while intoxicated.
Charles Goldenbeld   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Power Generation of Pure Sine Wave in Batteryless Solar System using Advanced Control

open access: yesPakistan Journal of Engineering & Technology, 2021
A novel technique for conversion of DC power to AC power is introduced using solar powered sine wave generation system is presented. DC power extracted from solar system is made utilitarian for driving the BLDC (brushless DC) motor with constant speed ...
Muhammad Siddique   +5 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

SYNTHESIS OF VOLTAGES OF UNIFORM PWM IN TIME REGULATION

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2014
The article describes a process of synthesis and qualitative assessment of the harmonic composition of voltages of multiple and single PWM pulses in time regulation, being, along with amplitude, frequency and phase method, one of control methods of an ...
A. G. Stryzhniou   +2 more
doaj  

Kendali Motor Induksi 3 Fasa Menggunakan Arduino Mega Berbasis HMI (Human Machine Interface)

open access: yesJurnal Teknik Elektro Indonesia, 2020
Motor induksi 3 Fasa merupakan jenis motor yang paling banyak digunakan untuk menggerakan berbagai beban/mesin. Dalam instalasinya, motor induksi 3 fasa dengan daya besar memerlukan rangkaian starting dan kendalinya seperti untuk membalik arah putaran ...
Eni Mariani Mariani, Hastuti hastuti
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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