Results 81 to 90 of about 204,612 (306)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Optimised design of electric actuators for more electric aircraft considering machining and assembly errors

IET Electric Power Applications
To the challenges posed by the complex structure and low reliability of existing hydraulic actuators used for more electric aircraft landing gear, this paper proposes an optimised design method for an electric actuator based on the principles of tubular ...
Wenlong Li, Qingle Wu, Guolai Yang, Chengyuan Guo   +3 more
doaj   +1 more source

Reduced-order observer analysis in MBPC techniques applied to the six-phase induction motor drives [PDF]

, 2015
Raúl Gregor, Jorge Rodas, Derlis Gregor and Federico Barrero (2015). Reduced-order Observer Analysis in MBPC Techniques Applied to the Six-phase Induction Motor Drives, Induction Motors - Applications, Control and Fault Diagnostics, Dr. Raul Gregor (Ed.),
(Coordinador), Barrero, Federico, Gregor, Derlis, Gregor, Raúl, Gregor, Raúl (Coordinador), Rodas, Jorge   +5 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Using AC Motors in Robotics

International Journal of Advanced Robotic Systems, 2008
It has been proven that fuzzy controllers are capable of controlling non-linear systems where it is cumbersome to develop conventional controllers based on mathematical modeling.
Hosein Marzi
doaj  

Multi‐level optimisation design of a yoke‐less axial‐field flux‐switching permanent magnet motor considering the fault‐tolerant capability

IET Electric Power Applications
This paper proposes a multi‐level optimisation design strategy aimed at enhancing the fault‐tolerant capability of a Yoke‐less Axial‐Field Flux‐Switching Permanent Magnet (YASA‐AFFSPM) motor.
Javad Rahmani‐Fard, Mohammed Jamal Mohammed   +1 more
doaj   +1 more source

Cross-Saturation Effects in IPM Motors and Related Impact on Sensorless Control [PDF]

, 2006
Permanent-magnet-assisted synchronous reluctance motors are well suited to zero-speed sensorless control because of their inherently salient behavior. However, the cross-saturation effect can lead to large errors on the position estimate, which is based ...
Guglielmi, Paolo, Pastorelli, Michele Angelo, Vagati, Alfredo   +2 more
core   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Variable-frequency inverter controls torque, speed, and braking in ac induction motors [PDF]

, 1974
Dc to ac inverter provides optimum frequency and voltage to ac induction motor, in response to different motor-load and speed requirements. Inverter varies slip frequency of motor in proportion to required torque.
Nola, F. J.
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source