Results 11 to 20 of about 43 (42)

Leveraging Data‐Driven and Fundamental Insights for Electrolyte Innovation in Lithium Metal Batteries

Advanced Materials, EarlyView.
Using 640 curated electrolyte formulations, we apply data‐driven analysis to reveal how molecular features govern coulombic efficiency (CE) in lithium metal batteries. Fluorine content correlates positively with CE, while oxygen, carbon, and higher boiling points correlate negatively.
Minh Van Duong, Mitchell Kaiser, Xia Cao, Trung Thien Nguyen, Au Nguyen, Phung My Loan Le, Jun Liu   +6 more
wiley   +1 more source

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Association of a single prior cesarean delivery with adverse birth outcomes at a tertiary referral hospital in southwestern Uganda: A secondary analysis of four observational studies

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Prior cesarean delivery (CD) is a leading indication for repeat CD and a key driver of rising cesarean rates in Sub‐Saharan Africa. Evidence on associations between prior CD and adverse outcomes in low‐resource settings remains limited.
Leevan Tibaijuka, Joseph Ngonzi, Katharine Correia, Jeffery A. Goldstein, James Z. Wang, Rachel E. Walker, Alison D. Gernand, Elias Kumbakumba, Adeline A. Boatin, Lisa M. Bebell   +9 more
wiley   +1 more source

Recent Advances (2023–2025) of Capillary Electrophoresis‐Mass Spectrometry (CE‐MS) for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu, David A. Alvarez Rodriguez, Noah Gould, Alexander R. Ivanov, Kevin Jooß, Liangliang Sun   +5 more
wiley   +1 more source

3D and 4D Free‐Breathing Abdominal T1‐Weighted MRI in Clinical Practice Using Deep Learning Auto‐Navigation and Reconstruction

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop and evaluate an automated clinical prototype for a 1‐min free‐breathing T1‐weighted 3D MRI and a 2.25‐min 4D MRI utilizing radial k‐space acquisition and deep learning (DL) auto‐navigation and reconstruction. Methods The clinical prototype was deployed on 3 T GE Healthcare scanners, using the GE DISCO‐Star (radial golden ...
Victor Murray, Yan Wen, Subin Erattakulangara, Oguz Akin, Richard Do, Gerald Behr, Zhigang Zhang, Arnaud Guidon, Ricardo Otazo   +8 more
wiley   +1 more source

The obsolescence of protected area categories in a polycrisis world

Conservation Biology, EarlyView.
Abstract Current global conservation models face significant limitations in addressing the global polycrisis, and the constraints of the International Union for Conservation of Nature protected area (PA) classification system are part of the issue. The principles of the new conservation paradigm—governance, equity, and interculturality—are not viable ...
Pamela Esther Degele
wiley   +1 more source

“I teach her at home”: Home learning environments amid resource constraints

Family Relations, EarlyView.
ABSTRACT Objective This study examined how mothers with low incomes think about and enact investments of time and money for their infants and toddlers. Background Infancy and toddlerhood are pivotal years for development. Home learning environments in these earliest years can also set the stage for later home learning environments.
Jill Hoiting, Sarah Halpern‐Meekin
wiley   +1 more source

Dolutegravir population pharmacokinetics in racially, sex‐ and age‐diverse and antiretroviral therapy‐experienced adults with HIV in the United States

HIV Medicine, EarlyView.
Abstract Objectives Dolutegravir (DTG) has been associated with weight gain in women with HIV, Black people with HIV and people with HIV60 years. This study aimed to characterise DTG population pharmacokinetics (PopPK) in a diverse population including these sub‐populations.
Adrian Khoei, Andrew Edmonds, Yen Chang, Catalina Ramirez, Mackenzie Vogan, Amanda Poliseno, Steven Wolinsky, Ken Ho, Todd T. Brown, Joseph B. Margolick, Jacquett Batson, Jennifer Hoffmann, Mark A. Marzinke, Mirjam‐Colette Kempf, Maria L. Alcaide, Joffi Effoe, Cecile D. Lahiri, Igho Ofotokun, Anandi N. Sheth, Stephen Gange, Audrey L. French, Bani Tamraz, Bradley E. Aouizerat, Phyllis C. Tien, Seble G. Kassaye, Jack DeHovitz, Kathryn Anastos, Kara W. Chew, Michelle Floris‐Moore, Julie B. Dumond   +29 more
wiley   +1 more source

An Electronic Health Record “Nudge” to Reduce Antipsychotic Medication Prescribing for Primary Care Patients With Dementia: A Pragmatic RCT

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background We hypothesized that an electronic health record (EHR) alert grounded in behavioral science could reduce new antipsychotic medication prescriptions for older adults with dementia. Methods We conducted a pragmatic clinical trial at a large academic health system, randomizing providers to receive the alert (intervention) or not ...
Catherine A. Sarkisian, Chad Wes Villaflores, Anne M. Walling, Sitaram S. Vangala, Eric M. Cheng, Suzanne Bliven Shu, Ajaya Pillai, Grace Y. Cheng, Noah Goldstein, John Mafi   +9 more
wiley   +1 more source

GloBIAS survey results – An insight into the global bioimage analysis community

Journal of Microscopy, EarlyView.
Abstract There is a global need for bioimage analysis (BIA) as advances in life sciences increasingly rely on cutting‐edge imaging systems that have dramatically expanded the complexity and dimensionality of biological images. Turning these data into scientific discoveries requires scientists with effective data management skills and knowledge of state‐
Laura R. de la Ballina, Christa G. Walther, Nicholas D. Condon, Alessandro A. Felder, Martin Schätz, Bettina Schmerl, Ko Sugawara, Clara Prats, Anna Klemm, Kota Miura, Paula Sampaio, Christian Tischer, Shuichi Onami, Rocco D'Antuono, Beth A Cimini, Robert Haase, Agustin A. Corbat, Florian Levet   +17 more
wiley   +1 more source