Results 81 to 90 of about 1,599,950 (264)

Strengthening Uganda's policy environment for investing in university development [PDF]

open access: yes
The authors examine the policy environment for investment in university development in Uganda, with special attention to the needs of Makerere University. They present data on the structure and financing of higher education, which gets a high priority in
Colletta, Nat   +7 more
core  

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

Академическая доброчестность в системе профессиональной подготовки будущего педагога [PDF]

open access: yes, 2018
У статті окреслено концептуальні основи формування академічної доброчесності у майбутніх педагогів під час професійної підготовки; досліджено суть поняття академічної доброчесності, його зміст стосовно формування особистісних та професійних характеристик
Сопова, Дана Олегівна
core  

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

open access: yesAdvanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong   +15 more
wiley   +1 more source

The practice of design as a vehicle for knowledge, between university and professional practice

open access: yesTechne
The education of architects is characterised by the integration of theoretical knowledge and professional practice. However, changes in the university system and the increasing specialisation of research have deepened the divide between academic training
Giiulia Vignati   +3 more
doaj   +1 more source

Combining Work and Study in Tatarstan Higher Education Institutions: How Academic Performance Is Affected?

open access: yesВопросы образования, 2014
Nowadays, combining work and study is typical for both low-income students and those who are well off. Such students have an array of reasons to start working, from the ambition to get integrated into the job market and build a career to the desire to ...
Diana Yanbarisova
doaj   +1 more source

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

Doctoral Degrees and the Academic Librarian, or, is "There a Doctor in the House?" [PDF]

open access: yes, 2006
Recently, discussions have emerged concerning newly minted Ph.D.s entering the professional field of librarianship. To be certain, these discussions have revolved around the potential entrance of Ph.D.
Hérubel, Jean-Pierre V. M.
core  

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang   +7 more
wiley   +1 more source

Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai   +12 more
wiley   +1 more source

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