From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A Survey of the Relationship between Academic Burnout and Academic Achievement of Dental Students of Guilan University of Medical Sciences [PDF]
Introduction: Students’ academic burnout has always been important. Not only it can affect students’ scientific destiny, but also it damages students’ mental health and leads to various failures. Due to important of academic burnout it students’ academic
M Falahchai +4 more
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Nickel–aluminum bronze (NAB) is increasingly used in marine applications, where components are subjected to combined cyclic loading and corrosive environments.
MohammadBagher Mahtabi +4 more
doaj +1 more source
Proposições metodológicas na intervenção com estudantes com queixa escolar
Esta pesquisa descreve uma experiência de intervenção envolvendo estudantes com histórico de fracasso escolar, desenvolvida em um serviço-escola, no curso de Psicologia.
Joyce Lúcia Abreu Pereira Oliveira +2 more
doaj +1 more source
The Survey of Educational Status and Some Related Factors in Students of Paramedical Faculty of Gonabad University of Medical Sciences [PDF]
Introduction: The educational status of students during their studies in universities is very important. Being aware of the shortcomings and factors related to the educational status and recognizing in a timely manner, it is possible to provide solutions
F Ghasemi Roshanavand +6 more
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Supplemental material, Supplemental_Materials_081718_FINAL for The Academic Response-to-Failure Scale: Predicting and Increasing Academic Persistence Post-Failure by Yael Zemack-Rugar, Canan Corus and David Brinberg in Journal of Marketing ...
Yael Zemack-Rugar (6288158) +2 more
core +1 more source
Eskola porrota hizkuntzen irakaskuntzan: motibazioaren azterketa hizkuntzen ebaluazioan irakasleen ikuspegitik [PDF]
This work examines the correlation of motivation, as a main cause of academic failure and an important concept behind the aforementioned group of reasons.
Endika Ibarguren, Mari Mar Boillos
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source

