Results 251 to 260 of about 3,824,378 (404)

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source

2‐line Ferrihydrite Enhance Microbial Synthesis of Plant Biostimulants in Composted Biosolid by Regulating Phyla Pseudomonadota and Actinomycetota

Advanced Science, EarlyView.
This study explores how iron and manganese oxides transform sewage sludge into plant biostimulants during composting. Non‐targeted identification reveals the main species of plant biostimulants. Metagenomic analysis reveals that 2‐line ferrihydrite specifically enriches microbial genes for biosynthesis, boosting plant‐growth promoters.
Yu Zhang, Ziwei Zhang, Zexu Chen, Boyuan Yang, Siying Cai, Jun Chen, Jianhua Guo, Weijun Zhang   +7 more
wiley   +1 more source

More efficient reproducible research in hydrology: moving research down the academic career scale (MRDTACS). [PDF]

Philos Trans A Math Phys Eng Sci
Hut R, Hall C.
europepmc   +1 more source

The use of Academic Library and Information Seeking Behavior of Students at Lusaka Apex Medical University

Dalitso Mvula, Matildah Muchinga
openalex   +2 more sources

Knowledge Discovery in a Review of Monograph Acquisitions at an Academic Health Sciences Library

, 2019
Marcos Alejandro Yánez Rodríguez
openalex   +2 more sources

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

The Sci-Hub Ban in India: When Copyright Collides with Clinical Reality. [PDF]

Indian J Crit Care Med
Ghatak T, Mani UA.
europepmc   +1 more source

Academic Library Instruction

College & Research Libraries, 1965
openaire   +2 more sources

FY2016 Integrated Postsecondary Education Data System (IPEDS) Academic Libraries Survey: University of Rhode Island Data

, 2017
Michael C. Vocino
openalex   +1 more source