Results 41 to 50 of about 103,094 (295)
Old News: Representation and Academic Novelty
The new outstrips the old—but only sometimes. This short paper identifies four forms of ‘novelty’ in Anglophone human geography. In taking the case of a nascent ‘nonrepresentational geography’ some concerns are raised about the seeming ennui with representation as a research issue and as a practical and political resource. Far from insisting that ‘old’
Castree, Noel, Macmillan, Thomas
openaire +4 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Academic Science News & Reviews March 1997 [PDF]
https://commons.library.stonybrook.edu/academic-science-news-reviews/1004/thumbnail ...
Stony Brook University. Academic Science News & Reviews.
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Thoughts on the Organization of Future International Conferences of Ethiopian Studies
Information ATTENTION: Due to copy-right no online publication is provided.
Donald N. Levine
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Academic Science News & Reviews December- January 1997-1998 [PDF]
https://commons.library.stonybrook.edu/academic-science-news-reviews/1001/thumbnail ...
Stony Brook University. Academic Science News & Reviews.
core
Citizen participation in news [PDF]
The process of producing news has changed significantly due to the advent of the Web, which has enabled the increasing involvement of citizens in news production.
Jonathan Scott +5 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Academic Science News & Reviews December- January 1996-1997 [PDF]
https://commons.library.stonybrook.edu/academic-science-news-reviews/1002/thumbnail ...
Stony Brook University. Academic Science News & Reviews.
core

