Results 71 to 80 of about 3,946,873 (324)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
In memoriam Gianfranco Fiaccadori (1957–2015)
Aethiopica, 2016 Obituary
Beatrice Daskas, Agostino Soldati
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
In memoriam Andrzej Zaborski (1942–2014)
Aethiopica, 2016 Obituary
David Appleyard
doaj +1 more source
The image of child protection social workers in the news and amongst children's professionals : a thesis presented in partial fulfilment of the requirements for the degree of Master of Social Work at Massey University, Manawatū, New Zealand [PDF]
, 2018 This research examines portrayals of child protection social workers in New Zealand news reporting and explores how child protection social workers are perceived by their colleagues in the children’s workforce.
Harding, Simon James
core
Old News: Representation and Academic Novelty
Environment and Planning A: Economy and Space, 2004 The new outstrips the old—but only sometimes. This short paper identifies four forms of ‘novelty’ in Anglophone human geography. In taking the case of a nascent ‘nonrepresentational geography’ some concerns are raised about the seeming ennui with representation as a research issue and as a practical and political resource. Far from insisting that ‘old’
Castree, Noel, Macmillan, Thomas
openaire +4 more sources
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
學術網路與圖書館資料徵集 Academic Networks and Library Acquisition Work [PDF]
Jiàoyù zīliào yǔ túshūguǎn xué, 1989 無By the news from local evening newspaper, The Library of Congress, Harvard University Harvard-yenching Library and Yale University Library will establish special collections for Chinese Democracy Movement, the author points out that information in ...
Hon-chu Huang
doaj