Development of a pediatric ophthalmology academic partnership between Canada and Ethiopia: a situational analysis. [PDF]
Kletke SN +4 more
europepmc +1 more source
Chitralekha Potnis, Ajit Potnis
openaire +2 more sources
Engineering a 660 nm‐Responsive Optogenetic Inducer of Pyroptosis for Precision Cancer Therapy
This study reports a bioorthogonal pyroptosis inducer, PyroRACS. By using a red‐light‐responsive Cre‐On genetic switch to control the expression of highly cytotoxic GSDMDNT, PyroRACS enables the artificial induction of pyroptosis with precise spatiotemporal control.
Mengkai Zhang +5 more
wiley +1 more source
Community-Academic Partnership to Assess the Role of Physical Disinvestment on Firearm Violence in Toledo, OH. [PDF]
Gause EL +3 more
europepmc +1 more source
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li +16 more
wiley +1 more source
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu +12 more
wiley +1 more source
Using action research and a community-academic partnership to understand clinical trial participation: a patient-centered perspective. [PDF]
Santarossa S +6 more
europepmc +1 more source
Nursing practice and global refugee migration: initial impressions from an Intergovernmental-Academic Partnership. [PDF]
Bampoh V +9 more
europepmc +1 more source
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu +9 more
wiley +1 more source
Improving health equity through sustained academic partnership: development of a maternal-fetal medicine fellowship training program in Western Kenya. [PDF]
Nding'ori D +13 more
europepmc +1 more source

