Results 101 to 110 of about 14,778,292 (313)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Barriers and enablers to participation in Immersion Therapy for people living with disability

open access: yesTranslational Exercise Biomedicine
This study explored the perceived barriers and enablers to participation in Immersion Therapy, a novel water-based intervention for people living with disability.
Romano Luke   +2 more
doaj   +1 more source

Mental health and academic performance: a study on selection and causation effects from childhood to early adulthood

open access: yesSocial Psychiatry and Psychiatric Epidemiology, 2020
An inverse relationship between mental health problems and academic achievement is a well-known phenomenon in the scientific literature. However, how and when this association develops is not fully understood and there is a lack of longitudinal ...
Sara Agnafors, Mimmi Barmark, G. Sydsjö
semanticscholar   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Quality of service attributes based hybrid decision-making framework for ranking cloud service providers under Fermatean fuzzy environment [PDF]

open access: yesYugoslav Journal of Operations Research
Cloud Computing has gained substantial popularity due to its ability to offer diverse and dependable computing services suited to clients demands. Given the rapid expansion of this technology, an increasing number of IT service providers are competing to
Al-Mashhadani Athraa Kamel   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

El logro académico estático y dinámico en matemática desde el modelo de las inteligencias múltiples

open access: yesEcomatemático, 2017
The present study analyses the relation between Multiple Intelligences (Logical-Mathematical, Verbal-Linguistic, Visual-Spacial, Musical-Rhythmic, Bodily-Kinesthetic, Interpersonal, Intrapersonal, Naturalist, their scales and
Sandra Mariel Intelisano
doaj   +1 more source

The Relationship Between Executive Functions and Academic Performance in Primary Education: Review and Meta-Analysis

open access: yesFrontiers in Psychology, 2019
The purpose of this study was to research the relationship between executive functions and academic performance in primary education (6–12 years). Based on 21 samples (n = 7,947), a meta-analysis of random effects demonstrated a moderately significant ...
Alejandra Cortés Pascual   +2 more
semanticscholar   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

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