Results 161 to 170 of about 213,509 (265)

Machine Learning‐Guided Engineering of Protein Phase Separation Properties in Immune Regulation

Advanced Science, EarlyView.
PScalpel, a machine learning model integrating protein structure extraction, graph contrastive learning, and a genetic algorithm, guides the engineering of protein phase separation ability. It adopts transfer learning methods to provide predictive recommendations for protein phase separation ability changes through single amino acid mutations in a ...
Chenqiu Zhang, Jia Wang, Zhe Wang, Liyan Zhu, Sihui Cai, Luzhi Zhan, Haorui Liang, Yaoxing Wu, Jianqiang Li, Jun Cui   +9 more
wiley   +1 more source

Does Teacher Support Scaffold Engagement? Academic Self-Efficacy as Mediator and Proactive Personality as Moderator Among Chinese High School Students. [PDF]

Behav Sci (Basel)
Sun W, Wu Q, Zhang X, He D, Liu X.
europepmc   +1 more source

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

The influence of parental educational expectations on primary school students' social-emotional competence: the chain mediation effect of peer relationships and academic self-efficacy. [PDF]

Front Psychol
Yang L, Chen K, Ma S, Lei Y.
europepmc   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

Advanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo, Yingge Lv, Shuyu Huang, Chang Liu, Yan Ouyang, Bei Lan, Chenghao Xuan   +6 more
wiley   +1 more source

The indirect associations of academic self-efficacy and brief fear of negative evaluation in the relationship between neurotic personality traits and test anxiety of medical sciences students. [PDF]

BMC Psychol
Lin L, Hongyu Y, Xing J, Ying M, Zixuan L, Tingting L.   +5 more
europepmc   +1 more source

Academic Success, Self-Efficacy, and Homework:

The Annual Report of Educational Psychology in Japan, 2018
openaire   +2 more sources

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

Advanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang, Pai Peng, Liang Song, Qiaoxuan Wang, Zilong Zhong, Dongchao Qiu, Yunfan Liu, Kefei Zhao, Xiaofei Dong, Changyou Gao   +9 more
wiley   +1 more source

The Effect of Academic Procrastination on Life Satisfaction Among Nursing and Midwifery Students: The Serial Mediation Role of Academic Self-Efficacy and Self-Control. [PDF]

Behav Sci (Basel)
Demir S, Kuşcu Karatepe H.
europepmc   +1 more source

The relationship among self-efficacy, academic self-efficacy, problem solving skills and foreign language achievement

, 2013
This study aims to scrutinize the possible relationship between Self-Efficacy (SE), Academic Self-Efficacy Beliefs (ASE), Problem Solving Skills (PSS) and Foreign Language Achievement (FLA) among prospective ELT teachers. To do so, the data for the study were collected through three questionnaires.
openaire   +2 more sources