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The pathophysiology of Acanthamoeba keratitis

Trends in Parasitology, 2006
Acanthamoeba keratitis is a sight-threatening infection of the ocular surface that is produced by several free-living amebae of the genus Acanthamoeba. Infection is usually initiated by Acanthamoeba-contaminated contact lenses and produces exquisite pain and ulceration of the ocular surface.
Daniel W. Clarke, Jerry Y. Niederkorn
openaire   +2 more sources

The immunobiology of Acanthamoeba keratitis

Microbes and Infection, 2006
Acanthamoeba spp. are free-living amoebae that cause Acanthamoeba keratitis, a blinding corneal infection. The innate immune apparatus is crucial for the resolution of the disease. With the exception of mucosal antibody, elements of the adaptive immune system fail to prevent infection or contribute to its resolution in experimental animals.
Daniel W. Clarke, Jerry Y. Niederkorn
openaire   +2 more sources

On Acanthamoeba keratitis

Orvosi Hetilap, 2008
Az Acanthamoeba-infekciók száma világszerte, így hazánkban is növekvő tendenciát mutat. A diagnosztikus és terápiás lehetőségek bővülése ellenére ez a betegség súlyosan károsíthatja a látást. A kórkép jellemzőit foglaljuk össze és mutatjuk be. A betegség elsősorban kontaktlencsét viselőkön alakul ki a nem megfelelő higiénia miatt.
András Berta   +3 more
openaire   +2 more sources

Treatment of Acanthamoeba keratitis

Vestnik oftal'mologii, 2016
In recent years, Acanthamoeba keratitis (AK) has became a clinically significant problem because of the broad use of contact lenses that are the major risk factor of the disease. The treatment presents considerable difficulties due to similarity of clinical manifestations of AK to other keratites (bacterial, herpetic, and fungal).
Evg A Kasparova, N R Marchenko
openaire   +3 more sources

Acanthamoeba Keratitis Versus Mixed Acanthamoeba and Bacterial Keratitis: Comparison of Clinical and Microbiological Profiles.

Cornea, 2020
PURPOSE To compare the clinical profiles and outcomes of patients with Acanthamoeba keratitis with or without mixed bacterial infection. METHODS A retrospective analysis of microbiologically confirmed AK cases presenting to a tertiary care center over ...
Arshi Singh   +3 more
semanticscholar   +1 more source

Diagnosis of Acanthamoeba keratitis

Vestnik oftal'mologii, 2016
The Acanthamoeba keratitis is a relatively rare, but dangerous disease of the cornea. Its development is thought to be associated with contact lens wearing as well as corneal microwounds contaminated with soil or water. The disease has no evident distinctive clinical features and is, therefore, difficult to be distinguished from herpetic or fungal ...
Evg A Kasparova, N R Marchenko
openaire   +2 more sources

Updates in Acanthamoeba Keratitis

Eye & Contact Lens: Science & Clinical Practice, 2007
Acanthamoeba keratitis is a potentially blinding microbial disease that has been increasing in incidence during the past two decades. Prognosis of this serious disease had been dismal, but improvement in diagnosis, a better understanding of the natural course of the disease, and recent introduction of multiple and effective therapeutic agents have ...
Harrison D Cavanagh   +4 more
openaire   +3 more sources

Painless Acanthamoeba keratitis

Canadian Journal of Ophthalmology, 2012
Acanthamoeba keratitis (AK) is known to cause sitethreatening ocular infections. Patients often have a history of improper cleaning of contact lenses (CTL), swimming, or using hot tubs while wearing contact lenses. The hallmark symptom of AK is exquisite pain, often out of proportion to the clinical picture.
Alexander C. Tokarewicz   +3 more
openaire   +3 more sources

Systemic Miltefosine as an Adjunct Treatment of Progressive Acanthamoeba Keratitis

Ocular immunology and inflammation, 2020
Purpose: To report our experience with oral miltefosine (MLT) as an adjunct treatment for progressive Acanthamoeba keratitis (AK). Methods: Retrospective case series of all patients who underwent treatment with oral MLT for AK at Bascom Palmer Eye ...
Andrea Naranjo   +4 more
semanticscholar   +1 more source

Bilateral Acanthamoeba Keratitis

American Journal of Ophthalmology, 2008
To determine the prevalence and characteristics of binocular involvement among patients with Acanthamoeba keratitis.Retrospective case series.Risk factors and outcomes of bilateral infection were explored among consecutive cases of Acanthamoeba keratitis diagnosed at a single institution from 1997 through mid 2007.Fifty eyes were confirmed to have ...
M. Bowes Hamill   +5 more
openaire   +3 more sources

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