In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei [PDF]
African trypanosomiasis is a major neglected tropical disease with significant health and economic concerns in sub-Saharan Africa. In the absence of vaccines for African trypanosomiasis, there is a consideration for alternative sources of chemotherapy ...
Aboagye Kwarteng Dofuor +4 more
doaj +3 more sources
Phytochemistry, Antioxidant, and Hepatoprotective Potential of Acanthospermum hispidum DC Extracts against Diethylnitrosamine-Induced Hepatotoxicity in Rats [PDF]
Background: Burkina Faso is classified among the countries with a high prevalence (˃12%) of hepatitis. Hepatic diseases, such as cirrhosis—related to alcoholism—and hepatitis B and C, are the cause of the increase in cases of liver cancer ...
Jotham yhi-pênê N'DO +1 more
exaly +4 more sources
Acanthospermum hispidum and Its Metabolite Stigmasterol Modulates Anti-Inflammatory Antagonism of COX-1 and TGF-β [PDF]
This study evaluates the anti‐inflammatory effect of Acanthospermum hispidum (AH) leaves and confirms its traditional use on diseases linked to inflammation. AH ethanol extract presents a dose‐dependent increase in anti‐inflammatory activity on the different times examined (T30 – T150). Also, stigmasterol present in AH shows potent antagonist influence
Epole Ntungwe +2 more
exaly +3 more sources
Acanthospermum hispidum DC. is a plant with extensive traditional use in folk medicine for treatment of various infections in Sudan including jaundice, stomach discomfort, constipation, and viral infections.
Asaad Khalid +2 more
exaly +3 more sources
Effect of Herbal Extracts on Antituberculosis Drug-Induced Hepatotoxicity: A Systematic Review. [PDF]
Background Tuberculosis (TB) remains a major global health challenge. While effective, first‐line antitubercular drugs such as isoniazid and rifampicin often cause hepatotoxicity, limiting treatment safety. Herbal extracts with antioxidant and hepatoprotective properties may help mitigate this liver damage.
Ravedar SM +6 more
europepmc +2 more sources
Regional variability in phytochemical profiles and bioactivities of macerate and decoction extracts from three medicinal plants of Burkina Faso [PDF]
IntroductionRegional variability in secondary metabolite biosynthesis represents a critical dimension of plant chemodiversity. This study examined Acanthospermum hispidum, Vitex simplicifolia, and Vetiveria nigritana collected from three ecological zones
Abdel Magid Arsène Ouoba +7 more
doaj +2 more sources
Medicinal Plants Traditionally Utilized in Ethiopia for the Treatment of Hypertension: A Systematic Review. [PDF]
ABSTRACT Introduction Around the world, hypertension is one of the main causes of illness. Bioactive chemicals found in plant‐derived compounds are abundant and can be used to treat a wide variety of illnesses. Providing up‐to‐date information on Ethiopian medicinal plants used to treat hypertension is the goal of this review.
Yiblet Y.
europepmc +2 more sources
Weed infestation is considered as one of the major biotic stresses of dryland crop production. Weed species occurrence, abundance, and densities differ due to spatial soil fertility variability, and management practices by farmers.
Justin Chipomho +6 more
doaj +2 more sources
Medicinal Plants Used for Combating Human Bacterial Diseases in Ethiopia: A Systematic Review. [PDF]
In Ethiopia, bacterial diseases cause the majority of illness and mortality. They have become great challenges to the country, and a great proportion of its population are utilizing medicinal plants as sources of medicine for fighting diseases. The aim of the present work was to present a compiled document to show the great potential of plants in ...
Alemneh D.
europepmc +2 more sources
Weed seed banks function as subterranean reserves that continuously replenish weed populations, driving future infestations on farms. This study examined how various crop management practices on smallholder farms influence the size and composition of ...
Juliet C. Murimwa +6 more
doaj +2 more sources

