Results 91 to 100 of about 519,139 (282)

On the Accelerated Failure Time Model for Current Status and Interval Censored Data [PDF]

open access: yes, 2004
This paper introduces a novel approach to making inference about the regression parameters in the accelerated failure time (AFT) model for current status and interval censored data. The estimator is constructed by inverting a Wald type test for testing a
Cai, Tianxi, Tian, Lu
core   +1 more source

A flexible parametric accelerated failure time model

open access: yes, 2020
Accelerated failure time (AFT) models are used widely in medical research, though to a much lesser extent than proportional hazards models. In an AFT model, the effect of covariates act to accelerate or decelerate the time to event of interest, i.e. shorten or extend the time to event.
Crowther, Michael J.   +2 more
openaire   +2 more sources

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt   +8 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Accelerated Failure Time Model to Explore the Perception Response Times of Drivers in Simulated Car-Following Scenarios

open access: yesJournal of Advanced Transportation, 2020
In the development of effective rear-end collision alarm systems, understanding the factors that influence the perception response times (PRT) of drivers is important for the design of a reasonable lead time for the warning (or intervention) of likely ...
Yingshi Guo   +5 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Failure pattern of dispersive soil slopes under the action of rainfall conditions

open access: yesAlexandria Engineering Journal
Dispersive soil slopes are widely distributed in Northeast China. To analyze the failure caused by such slopes under various rainfall conditions, section K27 of the road-cutting slope of the Sui-Da Expressway in Heilongjiang Province, China, is ...
Zechuang Li, Zhiyi Yin
doaj   +1 more source

Instrumental variable estimation for duration data [PDF]

open access: yes
In this article we focus on time-to-event studies with arandomised treatment assignment that may be compromised byselective compliance. Contrary to most of the extensive literatureon evaluation studies we do not consider the effect of thetreatment on ...
Bijwaard, G.E.
core   +1 more source

Identifying High‐Impact Solutions to Address Racial and Ethnic Health Disparities in Lupus: A Consensus‐Based Approach

open access: yesArthritis Care &Research, EarlyView.
Objective We conducted formative research aimed at identifying solutions that address inequitable health outcomes in lupus due to adverse social determinants of health (SDoH). Methods We conducted a search for keywords, which provided insights into potential solutions and initiatives underway. An advisory panel of lupus experts iteratively reviewed the
Joy Buie   +11 more
wiley   +1 more source

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