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Advanced Healthcare Materials, EarlyView.Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng +16 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
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Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Failure Lifetime Evaluation Based on Accelerated Generalized Wiener Degradation Process Models with Random Diffusion Coefficients. [PDF]
Entropy (Basel)Li S, Yan Z.
europepmc +1 more source
Multi-Target Radar Speed Meter Failure Mechanism Research. [PDF]
Sensors (Basel)Luo L +6 more
europepmc +1 more source
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Flexible parametric accelerated failure time model
Journal of Biopharmaceutical Statistics, 2021Accelerated Failure Time (AFT) models are viable alternatives to the Cox proportional hazard model, where failure times are explicitly modelled with respect to covariates. A major problem with parametric AFT models in practice is that statistical distribution used there often have a limited range of shapes, which may be inadequate to cope with real ...
Steve Su
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A homoscedasticity test for the accelerated failure time model [PDF]
Computational Statistics, 2018 The semiparametric accelerated failure time (AFT) model is a popular linear model in survival analysis. AFT model and its associated inference methods assume homoscedasticity of the survival data. It is shown that violation of this assumption will lead to inefficient parameter estimation and anti-conservative confidence interval estimation, and thus ...
Lili Yu, Liang Liu, Ding-Geng Chen
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A semi‐parametric accelerated failure time cure model
Statistics in Medicine, 2002AbstractA cure model is a useful approach for analysing failure time data in which some subjects could eventually experience, and others never experience, the event of interest. A cure model has two components: incidence which indicates whether the event could eventually occur and latency which denotes when the event will occur given the subject is ...
Chin-Shang, Li, Jeremy M G, Taylor
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Weighted accelerated failure time model [PDF]
The accelerated failure time (AFT) model is widely used in survival analysis and auxiliary information can be used to improve the efficiency of the model. We developed a weighted AFT model by using empirical likelihood probabilities as weights based on information from previous studies. The proposed model effectively overcomes the challenges associated
Nayaka Bandaralage, Ayesha Madhushani Rathnayake
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