Results 111 to 120 of about 1,225,869 (253)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Design and Implementation of Comparative Accelerated Life Test for Solder Joints Based on Failure Mechanism

open access: yes机车电传动, 2020
In order to solve the shortcomings of traditional accelerated life test, such as long test time and large sample size, it is necessary to design comparative accelerated life test.
Fan YANG
doaj  

Crack growth in Ti-8Al-1Mo-1V with real-time and accelerated flight by flight loading [PDF]

open access: yes
Crack growth in Ti-8Al-lMo-lV was measured and calculated for real time and accelerated simulations of supersonic airplane loading and heating. Crack-growth rates calculated on the assumption that an entire flight could be represented by a single cycle ...
Imig, L. A.
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

A NEW SPECTRUM DEVELOPMENT METHODOLOGY FOR ACCELERATED DURABILITY TEST

open access: yesJixie qiangdu, 2016
Loading spectrum acquired from proving ground contains a large percentage of low-amplitude loads. For accelerated durability test spectrum development,many small load omission criterions( SLOC) have been induced.
YU JiaWei   +4 more
doaj  

Design of Test Method for Analysis and Estimation of LED Luminaire Lifetime Performance Under Cycle Based Realistic Operating Conditions

open access: yesIEEE Access
LED-based lighting technology is widely adopted as it offers a range of benefits, including energy efficiency, durability, and flexibility in design. LED luminaires’ performance during their lifetime is always a concern as several subsystems are ...
Anjan N. Padmasali   +2 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Accelerated and real-time geosynchronous life cycling test performance of nickel-hydrogen batteries [PDF]

open access: yes
RCA Astro-Electronics currently has four nickel-hydrogen storage battery modules (11 cells each) on test in simulated geosynchronous life cycle regimes.
Green, R. S.
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy