Results 41 to 50 of about 1,225,869 (253)
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Reliability Modeling and Verification of Locking Mechanisms Based on Failure Mechanisms
ActuatorsThe locking mechanism is crucial for the reliable connection and disconnection of electrical connectors. Aiming at the lack of theoretical support for the reliability evaluation in long-term storage, a comprehensive multi-theory modeling method is ...
Ping Qian +5 more
doaj +1 more source
Deterioration of Teak Wood in Accelerated Decay Test
Floresta e Ambiente, 2019 The present study aimed to evaluate the biological resistance of teak (Tectona grandis) heartwood and sapwood to the action of Trametes versicolor and Gloeophyllum trabeum fungi in laboratory accelerated decay assays.
Weslley Candido de Oliveira +5 more
doaj +1 more source
Evaluation of Hemp Seed Oils Stability under Accelerated Storage Test
Antioxidants, 2022 The interest in hemp seed oil has recently increased, due to the latest regulations which allow its use as food. Hemp seed oil is characterized by a high content of polyunsaturated fatty acids, which are highly prone to oxidation.
Matilde Tura +4 more
doaj +1 more source
Multiple Charge State Beam Acceleration at Atlas [PDF]
, 2000 A test of the acceleration of multiple charge-state uranium beams was performed at the ATLAS accelerator. A 238U+26 beam was accelerated in the ATLAS PII linac to 286 MeV (~1.2 MeV/u) and stripped in a carbon foil located 0.5 m from the entrance of the ...
Nolen, J. A. +4 more
core +2 more sources
Critical self-organization of astrophysical shocks
, 2000 There are two distinct regimes of the first order Fermi acceleration at shocks. The first is a linear (test particle) regime in which most of the shock energy goes into thermal and bulk motion of the plasma. The second is an efficient regime when it goes
H. J. Völk +3 more
core +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Online test system for metro vehicle small electrical equipment accelerated test
Dianzi Jishu YingyongIn order to meet the requirements of online electrical performance parameter testing for various small electrical components of metro vehicles under the accelerated test， an online test platform for small electrical equipment of metro vehicles based on ...
Yin Hongquan
doaj +1 more source
Case Studies in Construction Materials, 2016 Macrocell corrosion test and accelerated alternating wet–dry experiment combined with marine field test were employed to study the corrosion behavior of HRB400 carbon steel, 1.5Cr steel, and 5Cr steel in a simulated concrete pore solution and mortar. The
Ming Liu +5 more
doaj +1 more source