Results 71 to 80 of about 1,225,869 (253)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Accelerated aging test in niger seeds

open access: yesJournal of Seed Science
:Niger is a promising oilseed species for biodiesel production but there is no much information about the physiological potential of its seeds. Thus, the aim was to adapt the methodologies of accelerated aging test on six lots of niger seeds.
Carla Regina Baptista Gordin   +2 more
doaj   +1 more source

Shear-free Null Quasi-Spherical Spacetimes [PDF]

open access: yes, 1997
The residual gauge freedom within the null quasi-spherical coordinate condition is studied, for spacetimes admitting an expanding, shear-free null foliation.
Bartnik R., Newman E. T., Robert Bartnik
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Study on Accelerated Stress Test for Fuel Cell Lifetime

open access: yesInternational Journal of Electrochemical Science, 2018
A practical accelerated stress test (AST) has been established to analyze the fuel cell durability in this work, which combines the actual operated conditions in fuel cell vehicle.
Tian Tian   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Accelerated Life Test Design for Tractor Powertrain Front Axle

open access: yesMATEC Web of Conferences, 2016
Accelerated Life Test (ALT) has been applied in the manufacturing for many years due to rapid changing technologies, more complex products, speedier product development, and more demanding customer requirements.
Ismail Azianti, Jung Won, Liu Qiang
doaj   +1 more source

Accelerated stress testing of thin film solar cells: Development of test methods and preliminary results [PDF]

open access: yes
If thin film cells are to be considered a viable option for terrestrial power generation their reliability attributes will need to be explored and confidence in their stability obtained through accelerated testing.
Lathrop, J. W.
core   +1 more source

Home - About - Disclaimer - Privacy