Results 81 to 90 of about 1,225,869 (253)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Vehicle accelerated corrosion test procedures for automotive in Malaysia
MATEC Web of Conferences, 2017 An accelerated corrosion test, known as proving ground accelerated test, is commonly performed by automotive manufacturers to evaluate the corrosion performance of a vehicle.
Anuar Liza +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2013 We model nanoflare heating of extrapolated active-region coronal loops via the acceleration of electrons and protons in Harris-type current sheets. The kinetic energy of the accelerated particles is estimated using semi-analytical and test-particle ...
Anastasiadis, A. +4 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Accelerated Life Test and Performance Degradation Test of Harmonic Drive with Failure Analysis
MachinesHarmonic drive is susceptible to strength failure and performance degradation failure during operation. Given the long life test cycles, limited sample size, and incomplete understanding of degradation laws, this study conducted comprehensive life test ...
Xian Zhang +5 more
doaj +1 more source
Accelerated degradation of silicon metallization systems [PDF]
Clemson University has been engaged for the past five years in a program to determine the reliability attributes of solar cells by means of accelerated test procedures.
Lathrop, J. W.
core +1 more source
Separation of accelerated electrons and positrons in the relativistic reconnection
, 2007 We study an acceleration of electrons and positrons in the relativistic magnetic field reconnection using a 2.5-D particle-in-cell electromagnetic relativistic code. We consider the model with two current sheets and periodic boundary conditions.
Karlicky, Marian
core +1 more source
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source