Results 41 to 50 of about 240,262 (268)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Dosage Forms Suitability in Pediatrics: Acceptability of Antibiotics in a German Hospital

open access: yesAntibiotics, 2023
Although drug acceptability can have a significant impact on patient adherence in pediatric therapy, data are limited, even for common therapeutic areas. We present the second part of an acceptability study conducted at the University Children’s Hospital
Viviane Klingmann   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Kualitas Terjemahan Kohesi Leksikal Repetisi dalam Cerita Anak Jenjang Pembaca Dini

open access: yesPrasasti: Journal of Linguistics
This study aims to find out the types of repetition and how they were translated in children-story books for emergent readers. The data were taken from five children story books, and they show the variety of repetitions.
Devanni Kusuma Putri, Sumarlam Sumarlam
doaj   +1 more source

Development, nutritional and microbial evaluation of cultured bovine milk supplemented with baobab fruit pulp

open access: yesCyTA - Journal of Food, 2023
Incorporation of the baobab fruit pulp in innovative formulations remains limited, despite its abundance of various nutrients and bioactive components.
Angela Wanjiku Mwangi   +2 more
doaj   +1 more source

Parental perceptions of a wearable vital signs monitor for observation of newborns: in-depth interviews in three tertiary hospitals, Southwest Nigeria

open access: yesFrontiers in Digital Health
IntroductionThe first 28 days of a newborn's life are a critical time for their survival and subsequent growth and development. Wearable devices have emerged as a potential solution for clinical monitoring, offering affordability, accessibility, and ...
Yetunde Olufisayo John-Akinola   +20 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Improving the Acceptability of Human Papillomavirus Vaccines Among Men Who Have Sex With Men According to the Associated Factors: A Systematic Review and Meta-analysis

open access: yesFrontiers in Pharmacology, 2021
Objectives: To investigate the acceptability of human papillomavirus (HPV) vaccination among men who have sex with men (MSM) and its associated factors.Methods: We searched studies written in English in PubMed, EMBASE, and Web of Science with no ...
Yang Zhao   +10 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Acceptance and acceptability criteria: a literature review

open access: yesCognition, Technology & Work, 2018
One of the common issues related to tool use is to know why certain tools are chosen, accepted and used by users, while others are rejected. The aim of this paper is to find out if there are criteria related to the tool that can explain this decision.
Alexandre, Boris   +3 more
openaire   +1 more source

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