Results 91 to 100 of about 303,253 (312)
Donor-Acceptor Cyclopropanes with an Amino Group as Donor
Over the last two decades, a renaissance has been witnessed in the research field of donor-acceptor (DA) cyclopropanes. Among all the subclasses of DA cyclopropanes, DA cyclopropanes with an amino group as donor (DA aminocyclopropanes) have drawn ...
Waser, Jerome, Wang, Ming Ming
core +1 more source
Intramolecular singlet fission (iSF) has shown potential to improve the power conversion efficiency in photovoltaic devices by promoting the splitting of a photon-absorbing singlet exciton into two triplet excitons within a single molecule.
Raimon, Fabregat +4 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Tuning the Electron Acceptor in Phthalocyanine‐Based Electron Donor–Acceptor Conjugates
AbstractZinc phthalocyanines (ZnPc) have been attached to the peri‐position of a perylenemonoimide (PMI) and a perylenemonoanhydride (PMA), affording electron donor–acceptor conjugates 1 and 2, respectively. In addition, a perylene‐monoimide‐monoanhydride (PMIMA) has been connected to a ZnPc through its imido position to yield the ZnPc‐PMIMA conjugate ...
Sekita, Michael +6 more
openaire +3 more sources
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Computations in Stochastic Acceptors
Machine learning provides algorithms that can learn from data and make inferences or predictions on data. Stochastic acceptors or probabilistic automata are stochastic automata without output that can model components in machine learning scenarios. In this paper, we provide dynamic programming algorithms for the computation of input marginals and the ...
openaire +2 more sources
A general approach is described for the formation of tetrahydrothiepines using donor-acceptor cyclopropanes. Thiochalcones, functioning as sulfur-containing four-atom building blocks, were reacted in a Lewis-acid-catalyzed formal (4+3)-cycloaddition ...
André U., Augustin +4 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Covalently Linked Donor-Acceptor Dyad for Efficient Single Material Organic Solar Cells
A novel covalently linked donor-acceptor dyad comprising a dithienopyrrol-based oligomeric donor and a fullerene acceptor was synthesized and characterized.
Tim, Leydecker +4 more
core +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source

