Results 51 to 60 of about 14,635,303 (266)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Assessing the benefit of the operating microscope and role of visual-spatial abilities in access cavity preparation performed by undergraduate students [PDF]

, 2003
Use of the operating microscope (OM) to improve undergraduate students' performance in access cavity preparation and canal location was assessed. Performance was also correlated to students' visual-spatial and psychomotor abilities.
Rampado, Michael Edward
core   +1 more source

The influence of the access cavity on the fracture resistance and life span of endodontically treated and permanently restored teeth: A systematic review

, 2022
The traditional endodontic access cavity (TradAC) preparation might result in increased the risk of the fracture of the tooth. Therefore, a growing interest on more contracted access cavities designs has emerged, aiming to preserve the maximum of tooth
chahid amina
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Access cavity in the 21th century

, 2022
In this study we understand what is the access cavity preparations and the error that might occur during this procedure. We also review the uptodate access cavity preparation methods.
Hadieh, Ghamari
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Guided Endodontics : A Novel Invasive Technique For Access Cavity Preparation -Review

International Journal of Research in Pharmaceutical Sciences, 2020
Precision medicine (PM) refers to the modifying of medical or dental treatment according to the individual features of each patient. Imaging has become a central part of PM since the last decade. PM takes into account and aims to exploit the specific profile of the patient’s unique biology and problem.
null Madhulika Chandak, null Manoj Chandak, null Chanchal Rathi, null Samrudhi Khatod, null Pooja Chandak, null Kajol Relan   +5 more
openaire   +1 more source

Influence of Endodontic Access Cavity Design on Fracture Strength of Teeth Restored with Bulk-fill and Fiber-reinforced Composites: An In vitro Study

Journal of International Clinical Dental Research Organization
Background: Preservation of tooth structure during endodontic access cavity preparation has gained importance due to its influence on the fracture resistance of endodontically treated teeth.
Sakshi Sharad Agrawal, S. R. Srinidhi, Sourabh S. Barbhai, Ayush A. Agarwal, Muskan Dilip Hinduja   +4 more
doaj   +1 more source