Results 141 to 150 of about 26,353,816 (299)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Report of the Privacy Public Records Access Study Committee.
Title from cover of PDF.; "October 25, 2007."; Includes document referred to on P. 2 and P. 9: Recommendation and Report of the Privacy and Public Access Subcommittee of the Supreme Court of Ohio Advisory Committee on Technology and the Courts on Public ...
Ohio. Privacy Public Records Access Study Committee.
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The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Approach for Wireless Resources Access Control Using User Localization
This paper describes research in field of wireless nodes indoor localization and controlling access to wireless network resources. Existing methods implement location based services and optionally allows controlling user access only at the authentication
Zagurskis, Valerijs +1 more
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
zk-Guard-R: Policy-Hidden and Replay-Safe zk-SNARK Access Control for IoT Sensor Data Stored on IPFS. [PDF]
Hou H, Ma Y, Zhao Z, Gan X.
europepmc +1 more source
Dakota Access Pipeline Project, Dakota Access, LLC
Path: C:\Users\rodor\Desktop\Roost_tree_Figures.mxd rewilliams 2/27/2015 COPYRIGHT© 2015 BURNS & McDONNELL ENGINEERING COMPANY. INC. u- ■ ( ‘ ^ '• ■' * ■ ■'' y' '', . 'v.y ■ ' fsmK"--':'s w.i :i--, (D'ia 'Vlf.
Dakota Access, LLC;
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