Results 111 to 120 of about 3,099,457 (245)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Theoretical Analysis of Vernier-Effect-Induced Sensitivity Enhancement of Dual Fiber Fabry-Pérot Cavities in OFDRs

open access: yesPhotonics
The vernier-effect-based sensitivity enhancement of two kinds of sensing units consisting of dual fiber Fabry-Pérot (FP) cavities in the Optical Frequency Domain Reflectometry (OFDR) is analyzed in this paper.
Mingxin Wang, Yueyu Xiao
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Ordinance on technical requirements and conditions of use of optical distribution networks of the Croatian regulatory agency - Analysis and outlook [PDF]

open access: yes
In September 2010 the Croatian regulatory agency (HAKOM) put in force the ordinance on technical requirements and conditions of use of optical distribution networks.
Brusić, Igor   +3 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

A successive variational mode extraction method based on spectrum trend and its application in non‐contact vital sign detection

open access: yesElectronics Letters
Detecting respiration and heartbeat information from human chest movement is crucial for non‐contact vital sign detection. Due to the small frequency difference between respiration and heartbeat signals and the relatively low amplitude of the heartbeat ...
Qianxi Zhao   +4 more
doaj   +1 more source

An access alternative for mobile satellite networks [PDF]

open access: yes
Conceptually, this paper discusses strategies of digital satellite communication networks for a very large number of low density traffic stations. These stations can be either aeronautical, land mobile, or maritime.
Wu, W. W.
core   +1 more source

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