Results 101 to 110 of about 100,540,696 (301)
PharmacyBackground: Limitations in timely and equitable access to essential medicines among older adults not only constitute a clinical barrier to the effective management of chronic conditions, but also represent a violation of the fundamental right to life ...
Doris Cardona +6 more
doaj +1 more source
HEALTH SERVICE REFORMS AND ACCESS TO SPECIALIST SERVICES [PDF]
Rheumatology, 1991 M A, Chamberlain, A, Tennant
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
POVERTY LEVELS MUST BE REDUCED TO IMPROVE ACCESSIBILITY TO HEALTH SERVICES
Jurnal Administrasi Kesehatan IndonesiaBackground: Access to health services is a fundamental right for every citizen, but its equitable distribution remains challenging due to the influence of several variables.
Desri Yesi +4 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Report from the Health Care Access Improvement Panel [2017]
, 2017 application/pdf; "May 2017.""2004 Senate Substitute for HB 2912 and House Substitute for SB 12 established the Health Care Access Improvement Program, which uses an annual assessment on inpatient services provided by hospitals to improve and expand ...
Health Care Access Improvement Panel (Kan.).
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Acesso e equidade nos serviços de saúde: uma revisão estruturada
Saúde em DebateRESUMO Artigo de revisão de literatura sobre a organização de serviços da Atenção Primária à Saúde em suas dimensões de acesso e equidade. Os artigos foram identificados nas bases de dados da Biblioteca Virtual em Saúde (Centro Latino-Americano e do ...
Fernando Passos Cupertino de Barros +3 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
BMC Public HealthBackground Poor access to health services endangers children’s health and development. Parents’ perspectives are essential for understanding barriers to children’s healthcare access, as they often serve as primary caregivers and decision-makers.
Nona Salimi +4 more
doaj +1 more source