Results 61 to 70 of about 96,865,685 (295)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Accessing Health Information and Health Services
European health communication is rich and diverse in terms of international perspectives, scientific approaches and topics. The ECREA Aarhus Best Papers special issue showcases this diversity. It features the best papers presented at the health communication section of the ECREA conference, which took place in Aarhus in 2022.
Rita Araújo, Julia C. M. Van Weert
openaire +4 more sources
Measuring access to health services: General Dental Services in Scotland [PDF]
Recently the issue of access to health services has been brought into sharp focus by clear evidence of rationing--patients queuing for NHS registration--in the NHS General Dental Services (GDS). Conventional estimates suggest that about 50% of adults are registered per annum.
Tilley, C. J., Chalkley, M. J.
openaire +4 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Accessibility and utilization of occupational health services
The purpose of this study was to evaluate employees' utilization of occupational health services in three Dutch companies in which the access to such services (open consultation hour, summoning and periodic health examination) is organized differently.
openaire +3 more sources
University students' access and use of sexual and reproductive health services in Australia
University attendance can lead to changes in sexual behaviour that place people at increased risk of negative sexual and reproductive health (SRH) experiences; however, relatively few studies have explored access to and use of SRH services by university ...
Ariana, Armin +19 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Access determinants and use of health services among the elderly
this study aimed to describe the characteristics related to access to and use of health services, and verify factors associated with the use of services among the elderly.
Darlene Mara dos Santos Tavares +5 more
doaj +3 more sources

