Results 51 to 60 of about 1,538,485 (265)
Access determinants and use of health services among the elderly
Bioscience Journal, 2017 this study aimed to describe the characteristics related to access to and use of health services, and verify factors associated with the use of services among the elderly.
Darlene Mara dos Santos Tavares +5 more
doaj +3 more sources
Effective access to health services: operationalizing universal health coverage
Salud Pública de México, 2015 The right to health and its operational form, as an organized social response to health: the right to health protection, are the mainstay for the global push towards universal health coverage.
Germán Fajardo-Dolci +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Improving access to refractive and eye health services
Community Eye Health Journal, 2016 Avoidable blindness and vision impairment affects 741 million people worldwide. Uncorrected refractive error (URE) is the major cause, accounting for 84% of all cases, or 625 million people. Despite URE being easily detected, measured and corrected, many
Luigi Bilotto +5 more
doaj
Substance Abuse Treatment, Prevention, and PolicyBackground Substance use disorders are prevalent among youth in sub-Saharan Africa (SSA), yet treatment resources are scarce. Peer provider delivered brief interventions (BIs) represent an affordable and potentially scalable strategy for addressing youth
Florence Jaguga +9 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Health and education: service providers in partnership to improve mental health
International Journal of Mental Health Systems, 2012 Background Children and adolescents from complex or disadvantaged backgrounds and multiple needs often are reluctant to seek help and this is particularly relevant in the context of mental health difficulties. Further, the complexity of the health system
Eapen Valsamma, Lee Lily, Austin Craig
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source