Results 51 to 60 of about 1,887,278 (338)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Measuring the Quality of Legal Aid Services as the Embodiment of Access To Justice
Jurnal Ilmiah Kebijakan Hukum, 2022 Since the enactment of Law Number 16 of 2011 concerning Legal Aid, the practice of legal aid services still has several problems including not being able to reach all districts/cities due to the limited number of Legal Aid Organizations that can provide ...
Oki Wahju Budijanto, Tony Yuri Rahmanto
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Access to Justice and Human Rights: A Comparative Study of Islamic Jurisprudence and Secular Legal Systems [PDF]
İnsan & ToplumThis study examines the conceptual frameworks of access to justice within Islamic and Western legal traditions. It provides a comprehensive overview of the evolution of access to justice discourse in both systems, aiming to develop a robust analytical ...
Büsra Gülsah
doaj +1 more source
The problems of access to justice in rural areas (on the example of Ukraine) [PDF]
SHS Web of Conferences, 2019 In this scientific article, problems of access to justice in rural areas in Ukraine are considered. It is proved that for the people living in rural areas it is necessary to consider access to justice as possibility of free application to justice system ...
Lapkin Andrii
doaj +1 more source
Nonlawyer Legal Assistance and Access to Justice [PDF]
, 1999 article published in law reviewNonlawyer legal assistance is a necessary ingredient of any plan for meaningful access to the courts. The American Bar Association Commission on Nonlawyer Practice found in 1995 "that as many as 70% to 80% or more of low ...
Hurder, Alex J.
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Proxy models of legal need: can they contribute to equity of access to justice? [PDF]
, 2006 Prioritisation of cases and resources as a means of rationing the limited legal aid budget has recently become a feature of access to justice in the UK. This article explores the utility of devising proxymodels of ‘legal need’ as a means of enabling the ...
Baker, DJ, Barrow, S
core +1 more source