Results 51 to 60 of about 50,066 (214)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

Access to Environmental Justice in Brazil

open access: yesInternational Journal for Court Administration, 2017
: This article aims to show how the equal access to environmental justice occurs in Brazil, even with litigants in inequality, with discrimination on the environmental matter, problems with interpretation of the law and few jurisprudence and information.
Mariana Passos Freitas
doaj   +1 more source

Access to Justice Due to the Covid-19 Pandemic

open access: yesIus Humani, 2020
The coronavirus pandemic (Covid-19) has caused many challenges to democracy around the world. Under the new conditions, states must implement effective quarantine measures, as well as take decisions that justifiably and least restrict human rights.
Nelli Golubeva   +2 more
doaj   +1 more source

Access to Administrative Justice as an Administrative Law Value: Designing an Inclusive and Accessible Administrative Justice System

open access: yesWindsor Yearbook of Access to Justice
The constantly developing norm of access to justice is moving to occupy a central place in the administrative justice system,  prompting a need to rethink the values that should serve to animate the system.
Laverne Jacobs
semanticscholar   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Generative AI and Access to Justice in Canada: The Case of Self-Represented Litigants [SRLs]

open access: yesWindsor Yearbook of Access to Justice
This article examines generative AI’s influence from the perspective of SRLs, exploring the potential and limitations of Large Language Model [LLM] usage by this category of litigants.
Fife Ogunde
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Reducing The “Justice Gap” Through Access to Unbundled Legal Services: Utilizing an A2J Measurement Framework to Measure Unbundling Effectiveness

open access: yesWindsor Yearbook of Access to Justice
The ever-growing disparity between the cost of legal services and Canadians’ ability to pay for those services is known as the “justice gap.” As that gap widens, stakeholders must look for innovative ways to address it. In recent years, the potential for
Brea Lowenberger   +2 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

More lawyers, more litigation?

open access: yesOñati Socio-Legal Series, 2021
This brief paper explores the correlation and potential relationship between the composition of the legal profession and trends in litigation, in Ontario, Canada.
Avner Levin, Asher Alkoby
doaj   +1 more source

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