Results 71 to 80 of about 555,884 (236)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender   +17 more
wiley   +1 more source

Enhancing digital road networks for better transportation in developing countries

open access: yesTransportation Research Interdisciplinary Perspectives
Data scarcity in developing countries often poses significant challenges to the use of analytics in addressing development issues. In transportation research, digitized road data is one of the most fundamental data structures, and a poorly digitized road
V.F. Stienen   +3 more
doaj   +1 more source

Access to medicines for acute illness in middle income countries in Central America [PDF]

open access: yes, 2013
OBJECTIVE To analyze the main predictors of access to medicines for persons who experienced acute health conditions. METHODS This was a cross-sectional analytic study, based on data from household surveys.
Camacho, Luiz Antonio Bastos   +3 more
core   +4 more sources

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers   +5 more
wiley   +1 more source

Judicial litigations and social welfare: access to medicines in two towns in the Santa Catarina State, Brazil - 10.4025/actascihealthsci.v34ispec.10084

open access: yesActa Scientiarum. Health Sciences, 2012
The growing number of lawsuits to obtain free medicines from the Brazilian Health System (SUS) is analyzed to characterize the supply of the requested drugs in two towns with different social and economic characteristics and different municipal ...
Silvana Nair Leite   +2 more
doaj   +1 more source

Improving the Evaluation and Management of Transfusion‐Related Iron Overload in Children, Adolescents, and Young Adults Following Cancer Treatment or Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell   +3 more
wiley   +1 more source

Changes in essential cancer medicines and association with cancer outcomes: an observational study of 158 countries

open access: yesBMC Cancer
Background Cancer is a major cause of mortality worldwide, and differences in cancer mortality rates between countries are, in part, due to differences in access to cancer care, including medicines.
Moizza Zia Ul Haq   +5 more
doaj   +1 more source

The Doha Declaration Ten Years on and Its Impact on Access to Medicines and the Right to Health [PDF]

open access: yes, 2011
Access to medicines is a human right, enshrined in legally binding international human rights treaties, select regional agreements and numerous national constitutions. The realization of access to medicines, including antiretroviral treatment, as part of
Correa, C, Matthews, DN
core  

Availability, price, and affordability of essential medicines to manage noncommunicable diseases : a national survey from Nepal [PDF]

open access: yes, 2019
The aim of this study was to evaluate the availability, price, and affordability of essential noncommunicable disease (NCD) medicines in Nepal. A cross-sectional survey was conducted in Nepal in 2015 using World Health Organization/Health Action ...
Ewen, Margaret   +4 more
core   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Home - About - Disclaimer - Privacy