Results 111 to 120 of about 6,446,081 (305)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Accesul la informaţiile de interes public – obligaţie legală în sarcina autorităţilor administraţiei publice. Studiu de caz privind gradul de accesibilitate al informațiilor de interes public comunicate din oficiu

Revista Transilvană de Ştiinţe Administrative, 2014
Acces to information of public interest has be-come, in the recent years, one of the most important criterion, according to which a society is assessed as a functional democracy, and, at the same time, is one of the fundamental principles of citizens ...
Ana Elena RANTA
doaj  

The Changing Public Role in Services to Agriculture: The Case of Information [PDF]

The paper analyzes the changes that have taken place in the nature of agriculture information and their consequences on the public role of related public services with specific regard to process undergoing in the European Union.
Zezza, Annalisa
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Access to Administrative Documents and to Public Sector Information in Italy [PDF]

, 2018
Law No. 241 of 1990 on administrative procedure (Italian APA) established general rules on the right of access to administrative documents for the first time in the Italian legal system, which partly reproduced rules defined in sectorial legislations. From such very restrictive regime of access to administrative documents—lately accompanied by a rather
openaire   +1 more source

Do NHS libraries have a role in providing information to patients, carers and the public? [PDF]

, 2008
Ten years ago, the UK government outlined a strategy that aimed to ‘ensure that patients, carers and the public have the information necessary to make decisions about their own treatment and care’ and suggested that the ‘NHS has a major responsibility ...
Brettle, A, Ormandy, P
core  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Internet Access: An Easy Solution for a Tough Problem [PDF]

, 2008
The city of Buffalo should create and advertise a single website that provides access and links to all public information about Housing Court cases, housing violations and housing permits to promote community involvement and serve as an early warning ...
Clarke, Janette
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Well-informed citizens and access to public sector information

Hrvatska i komparativna javna uprava : časopis za teoriju i praksu javne uprave, 2009
Pristup informacijama javnog sektora važan je za ostvarenje javnosti uprave i onoga što radi vlast. Pravo na pristup tim informacijama inovacija je koja se širi iz skandinavskih zemalja u SAD i ostatak Europe. Hrvatska je uzakonila takvo pravo 2003. U radu se analiziraju važeći međunarodni pravni dokumenti, kao i oni koji se tek pripremaju.
openaire   +1 more source