Results 161 to 170 of about 570,943 (217)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Multi-modal dissection of cell-type specific TDP-43 pathology in the motor cortex. [PDF]

Nat Commun
Ruf WP, Kühlwein JK, Meier L, Brockmann SJ, LeeBae J, Sadri-Vakili G, Yilmazer-Hanke D, Petri S, Thal DR, Grozdanov V, Danzer KM.   +10 more
europepmc   +1 more source

High-throughput single-cell DNA methylation and chromatin accessibility co-profiling with SpliCOOL-seq. [PDF]

Clin Transl Med
Shen Q, Deng E, Luo L, Zhang J, Yang Q, Su D, Fan X.   +6 more
europepmc   +1 more source

Oxidized LDL Induces Pro-Inflammatory Transcriptomic and Epigenomic Responses in Human CD4⁺ T Cells. [PDF]

FASEB J
Brown TA, Chalisey A, Jiang J, O'Callaghan CA.   +3 more
europepmc   +1 more source

Chromatin accessibility directly governs flavonoid biosynthesis and indirectly orchestrates cannabinoid production in <i>Cannabis</i>. [PDF]

Front Plant Sci
Ma Y, Wei X, Zhou W, Xie A, Chen Y, Yang C, Chen L, Dong L, Ning K.   +8 more
europepmc   +1 more source

Chromatin accessibility and transcriptome in human neuronal model exposed to Parkinson's environmental toxins. [PDF]

Sci Data
Hong J, Huang J.
europepmc   +1 more source