Results 161 to 170 of about 939,166 (317)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Quantifying racial inequality in transit access across New York City. [PDF]

PNAS Nexus
Zhang Y, Xu F, Talen E, González MC, Li Y.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Neural stem cell epigenomes and fate bias are temporally coordinated during mouse cortical development. [PDF]

Genes Dev
Shapira Y, Noack F, Vangelisti S, Chong F, Lifshitz A, Tanay A, Bonev B.   +6 more
europepmc   +1 more source

Potential accessibility - an interesting conceptual framework to address strategic planning issues in the Amsterdam region? [PDF]

It is difficult to prove a direct causal link between the spatial patterns of economic activities and the quality of the transport system. But it seems obvious that the transport system creates conditions, which enable economic activities to interact ...
Thomas Straatemeier
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Accessibility and the digital media

openL'accessibilità nei media digitali è diventata una preoccupazione critica, che influenza milioni di utenti in tutto il mondo. Questa ricerca esplora l'attuale panorama delle funzionalità di accessibilità nei media digitali, esaminando anche il ...
ABDIN, MOUNIR
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

A Scoping Review and Content Analysis of Available Chronic Pain Education Programs and Resources for Children, Adolescents and Young Adults with Diverse Abilities. [PDF]

J Pain Res
Smith MG, Schaly S, Berryman C, Khillan A, Ostojic K, Harvey A.   +5 more
europepmc   +1 more source

Application of gamification elements in accessibility testing

reservedThe concept accessibility means that a device, a service, a resource or an environment must be easily perceivable and usable by any user. More specifically, Web Accessibility means that the Web is designed so that everyone even people with ...
LLESHI, GERTA
core