Results 211 to 220 of about 1,872,650 (338)

A comprehensive evaluation of life sciences data resources reveals significant accessibility barriers. [PDF]

open access: yesSci Rep
L'Yi S   +7 more
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Professional and service-user perspectives regarding the future of mental healthcare in Israel. [PDF]

open access: yesIsr J Health Policy Res
Kramer A   +4 more
europepmc   +1 more source

Solvent accessibility in folded proteins. Studies of hydrogen exchange in trypsin

open access: hybrid, 1975
Clare Woodward   +2 more
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Supporting Communication Access of People With Communication Disabilities and Communication Differences in UNCRPD-Ratified Countries: An Integrative Review. [PDF]

open access: yesInt J Lang Commun Disord
Kearns Á   +9 more
europepmc   +1 more source

Identifying optimal locations for street experiments: A digital case study in Bologna

open access: yesJournal of Urban Mobility
This paper examines the integration of digital urban planning tools to identify optimal locations for street experiments, considering multiple parameters.
Corneel Casier   +7 more
doaj  

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