Results 221 to 230 of about 682,030 (316)

The universally accessible intersection

, 2015
Andre Frieslaar, P. Thompson, R. Frieslaar   +2 more
openalex   +1 more source

Location of logistics companies: a stated preference study to disentangle the impact of accessibility

, 2015
Ann Verhetsel, Roselinde Kessels, Peter Goos, Toon Zijlstra, Nele Blomme, Jeroen Cant   +5 more
openalex   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Computational Analyses and Challenges of Single-cell ATAC-seq. [PDF]

Genomics Proteomics Bioinformatics
Wang C, Zhou J, Zhang H, Zhuang Z, Bai G, Tang M, Liu S, Liu T.   +7 more
europepmc   +1 more source

The Effect of Volume Change on the Accessible Capacities of Porous Silicon-Graphite Composite Anodes

, 2019
Drew Joseph Pereira, John W. Weidner, Taylor R. Garrick   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Multi-omics profiling of chromatin accessibility and H3K27ac reveals super-enhancer-mediated regulatory networks governing endometrial receptivity in goats. [PDF]

J Anim Sci Biotechnol
Sun Z, Zhao J, Liao Y, Cheng Y, Yu H, Wang M, Fang X, Yang S, Zhao Y.   +8 more
europepmc   +1 more source

Implementation of Accessibility Standards in the Process of Course Design in Virtual Learning Environments

, 2012
Héctor R. Amado-Salvatierra, Rocael Hernández, José Ramón Hilera   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A DeepSeek cross-modal platform for personalized art education in Autism Spectrum Disorder. [PDF]

Sci Rep
Ding Y, Li Z, Zou Y, Dong X.
europepmc   +1 more source