Results 251 to 260 of about 1,872,650 (338)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Accessibility and influencing factors of leisure agriculture demonstration sites in Guangdong Province based on GWR model. [PDF]

Sci Rep
Liao Z, Zhang L.
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Development of a personalized conversational health agent to enhance physical activity for blind and low-vision individuals. [PDF]

Mhealth
Choi S, Seo J, Krishnan A, Kamath S, Kitsiou S, Haegele J.   +5 more
europepmc   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Confronting the public health challenge of inaccessible COVID-19 home tests: insights from the RADx® Tech Accessibility Initiative. [PDF]

Front Public Health
Kennedy EB, Noble K, Leite K, Downing M, Dolphin S, Cirrincione M, Walsh B.   +6 more
europepmc   +1 more source

Pensamentos, Emoções de um Grupo de Cadeirantes frente aos Problemas causados pela Falta de Acessibilidade nas Universidades/Thoughts, Emotions of a Group of College Wheelchair facing the Problems Caused by Lack of Accessibility in the Universities

, 1970
María Cecilia Ferreira Prado, Patrícia Costa dos Santos da Silva, Simone Cristina da Costa Ferreira, Míriam Monteiro de Castro Graciano, Evelise Aline Soares, Gema Mesquita   +5 more
openalex   +2 more sources

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

The relationship between accessibility of urban and rural high schools and enrollment rate: A county-level study. [PDF]

PLoS One
Li X, Mahdzar SSS, Khaidzir KAM, Ismail IE.   +3 more
europepmc   +1 more source

Accessibility

, 2016
openaire   +3 more sources