Results 271 to 280 of about 1,872,650 (338)

DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts. [PDF]

Nat Immunol
Beumer N, Imbusch CD, Kaufmann T, Schmidleithner L, Gütter K, Stüve P, Marchel H, Weichenhan D, Bähr M, Ruhland B, Marini F, Sanderink L, Ritter U, Simon M, Braband KL, Voss MM, Helbich SS, Mihoc DM, Hotz-Wagenblatt A, Nassabi H, Eigenberger A, Prantl L, Gebhard C, Rehli M, Strieder N, Singh K, Schmidl C, Plass C, Huehn J, Hehlgans T, Polansky JK, Brors B, Delacher M, Feuerer M.   +33 more
europepmc   +1 more source

Operational method for demonstrating fuel loading integrity in a reactor having accessible /sup 235/U fuel

, 1979
D.R. Ward
openalex   +2 more sources

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML. [PDF]

J Transl Med
Li XP, Gao Y, Zhao BT, Dai YT, Mao JY, Liang Y, Jiang L.   +6 more
europepmc   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Does Memory Accessibility Affect How Much We Learn from Studying? [PDF]

Behav Sci (Basel)
Kornell N.
europepmc   +1 more source

Acyl coenzyme A:cholesterol acyl transferase in macrophages utilizes a cellular pool of cholesterol oxidase-accessible cholesterol as substrate.

, 1988
Ira Tabas, William J. Rosoff, George Boykow   +2 more
openalex   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Spatial transcriptomics deconvolution methods generalize well to spatial chromatin accessibility data. [PDF]

Bioinformatics
Ouologuem S, Martens LD, Schaar AC, Shulman M, Gagneur J, Theis FJ.   +5 more
europepmc   +1 more source