Results 51 to 60 of about 1,855,697 (337)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

From ‘publish or perish’ to ‘publish with purpose’: perspectives from young adults with lived and living experience on transforming academic publishing in patient-oriented research

open access: yesResearch Involvement and Engagement
Background This commentary article critically assesses the inclusion and recognition of young adults with lived and living experiences (YALLE) in academic publishing.
Sandy Rao   +6 more
doaj   +1 more source

Factors Influencing the Formation of Salicylic Acid by Bipolar Membranes Electrodialysis

open access: yesMembranes, 2022
Salicylic acid is an intermediate product in the synthesis of dyes, medications and aspirin. An electrodialysis module has been constructed with commercial cationic, anionic and bipolar membranes for the conversion of sodium salicylate into salicylic ...
Juan Taumaturgo Medina-Collana   +3 more
doaj   +1 more source

Measuring Regional Cohesion Effects of Large-scale Transport Infrastructure Investments: An Accessibility Approach. [PDF]

open access: yes, 2008
Cohesion is considered one of the main policy goals both at a EU an national level. However, there is currently a lack of a common approach to measure cohesion effects of large-scale transport infrastructure investments.
Gomez, Gabriel   +2 more
core   +2 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Evaluation of accessible design of public transport facilities [PDF]

open access: yes, 2004
Today, accessibility for transport is an important issue to maintain the sustainability of our society. Laws and regulations order all new transport facilities be accessible, and transport companies are now trying to introduce accessibility into ...
Fujiyama, T.
core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Accessibility percolation with backsteps [PDF]

open access: yes, 2014
Consider a graph in which each site is endowed with a value called \emph{fitness}. A path in the graph is said to be "open" or "accessible" if the fitness values along that path is strictly increasing.
Berestycki, Julien   +2 more
core  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Accessibility of Vendor-Created Video Tutorials for People with Disabilities [PDF]

open access: yes, 2016
Many video, screencast, webinar, or interactive tutorials are created and provided by vendors for use by libraries to instruct users in database searching.
Oud, Joanne
core   +1 more source

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