Results 71 to 80 of about 651,025 (323)

Revisiting VR training in developmental disorders, is it a friend or foe? A scoping systematic review of randomized controlled trials

open access: yesEgyptian Pediatric Association Gazette
Background Immersive and non-immersive VR technology has been increasingly employed in training. This has encouraged physicians working in skill development to try using it to improve the learning, emotional recognition, and social skills of various ...
Antoine Fakhry AbdelMassih   +5 more
doaj   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

A Study on Lower Limb Movement Intention Recognition Based on Multi-Source Information Fusion

open access: yesIEEE Access
In order to enhance the suppleness of a lower limb rehabilitation medical robot during the re-habilitation process, this study proposes a multi-source information fusion lower limb motion intention recognition method based on surface electromyographic ...
Siyu Zong   +6 more
doaj   +1 more source

Access Patterns for Robots and Humans in Web Archives [PDF]

open access: yesarXiv, 2013
Although user access patterns on the live web are well-understood, there has been no corresponding study of how users, both humans and robots, access web archives. Based on samples from the Internet Archive's public Wayback Machine, we propose a set of basic usage patterns: Dip (a single access), Slide (the same page at different archive times), Dive ...
arxiv  

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Finite determination of accessibility and geometric structure of singular points for nonlinear systems [PDF]

open access: yesarXiv, 2019
Exploiting tools from algebraic geometry, the problem of finiteness of determination of accessibility/strong accessibility is investigated for polynomial systems and also for analytic systems that are immersible into polynomial systems. The results are constructive, and algorithms are given to find the maximum depth of Lie brackets necessary for ...
arxiv  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Modeling Access Differences to Reduce Disparity in Resource Allocation [PDF]

open access: yes
Motivated by COVID-19 vaccine allocation, where vulnerable subpopulations are simultaneously more impacted in terms of health and more disadvantaged in terms of access to the vaccine, we formalize and study the problem of resource allocation when there are inherent access differences that correlate with advantage and disadvantage.
arxiv   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

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