Results 71 to 80 of about 1,855,697 (337)

Planning virtual and hybrid events: steps to improve inclusion and accessibility [PDF]

Geoscience Communication
The past decade has seen a global transformation in how we communicate and connect with one another, making it easier to network and collaborate with colleagues worldwide. The COVID-19 pandemic led to a rapid and unplanned shift toward virtual platforms,
A. L. Doran, A. L. Doran, V. Dutch, V. Dutch, B. Warren, R. A. Watson, R. A. Watson, K. Murphy, A. Aldis, I. Cooper, C. Cockram, D. Harp, M. Desmau, M. Desmau, L. Keppler, L. Keppler   +15 more
doaj   +1 more source

Assessment of the Employment Accessibility Benefits of Shared Autonomous Mobility Services [PDF]

, 2020
The goal of this study is to assess and quantify the potential employment accessibility benefits of Shared Autonomous Mobility Service (SAMS) commute modes across a large diverse metropolitan region considering heterogeneity in the working population. To
Ahmed, Tanjeeb, Ghaffar, Arash, Hyland, Michael, PhD, Mitra, Suman, PhD, Sarma J S, Navjyoth   +4 more
core  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Upper Limb Motor Skills Performance Evaluation Based on Point-and-Click Cursor Trajectory Analysis: Application in Early Multiple Sclerosis Detection

IEEE Access, 2019
We present an enhanced version of the input device evaluation application (IDEA) system as an objective method for evaluating upper limb motor skills performance.
Nikolaos Papatheodorou, Alexandros Pino, Georgios TH. Kouroupetroglou, Vasilios Constantinides, Elisabeth Andreadou, Charalambos C. Papageorgiou   +5 more
doaj   +1 more source

Guidance on the principles of language accessibility in National Curriculum Assessments : research background [PDF]

, 2012
This review accompanies the document, which describes the principles which should guide the development of clear assessment questions. The purpose of the review is to present and discuss in detail the research underpinning these principles.
Dahlia Janan,, Wray, David
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

CAPTCHA Accessibility Study of Online Forums [PDF]

, 2011
The rise of online forums has benefited disabled users, who take advantage of better communications and more inclusion into society. However, even with accessibility laws that are supposed to provide disabled people the same equal access as non-disabled ...
Barnes, Sue, Kuzma, Joanne, Oestreicher, Klaus   +2 more
core   +2 more sources

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Proximity-centred accessibility—A conceptual debate involving experts and planning practitioners

Journal of Urban Mobility, 2023
Recognised as an important dimension of quality of life, accessibility has gained increasing attention from research and planning practice in the last decades.
Cecília Silva, Benjamin Büttner, Sebastian Seisenberger, Anna Rauli   +3 more
doaj  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source