Results 101 to 110 of about 4,064,536 (382)

Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity

open access: yesiScience, 2019
Summary: DNA accessibility is a key dynamic feature of chromatin regulation that can potentiate transcriptional events and tumor progression. To gain insight into chromatin state across existing tumor data, we improved neural network models for ...
Kamil Wnuk   +6 more
doaj  

Time frame as a determinant of accessibility of anaphoric demonstratives in Classical Arabic

open access: yesTopics in Linguistics, 2018
The aim of this paper is to investigate the determinants for choosing nominal anaphoric demonstratives in Classical Arabic (CA) by examining their usage in a corpus of CA texts.
Jarbou Samer Omar
doaj   +1 more source

Understanding and supporting web developers: : design and evaluation of a web accessibility information resource (WebAIR) [PDF]

open access: yes, 2016
This paper describes the design and evaluation of a Web Accessibility Information Resource (WebAIR) for supporting web developers to create and evaluate accessible websites.
Petrie, Helen   +2 more
core  

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

The case of the missing ‘If’: Accessibility relations in Stalnaker’s theory of conditionals [PDF]

open access: yes
A part of Stalnaker (1968)’s influential theory of conditionals has been neglected, namely the role for an accessibility relation between worlds. I argue that the accessibility relation does not play the role intended for it in the theory as stated, and ...
Mandelkern, Matthew
core  

Population need and geographical access to general practitioners in rural New Zealand [PDF]

open access: yes, 2004
To use a geographical information system (GIS) approach to demonstrate the extent to which different areas in New Zealand vary in their geographical access to GPs, and to analyse the extent to which spatial access varies in relation to different ...
Barnett, A. Ross, Brabyn, Lars
core   +1 more source

Effect of a Web-Based Behavior Change Program on Weight Loss and Cardiovascular Risk Factors in Overweight and Obese Adults at High Risk of Developing Cardiovascular Disease: Randomized Controlled Trial. [PDF]

open access: yes, 2015
Web-based programs are a potential medium for supporting weight loss because of their accessibility and wide reach. Research is warranted to determine the shorter- and longer-term effects of these programs in relation to weight loss and other health ...
Alanna McGrath   +14 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

A Spatial analysis on the relation between accessibility and spatial development for Cross-border regions [PDF]

open access: yesInvestigaciones Regionales - Journal of Regional Research, 2011
Cross-border regional development is one of the EU current major concerns. These regions are usually less dynamic socio-economically. Some of them have recently benefited from new roads, which have mainly been funded through the European financial ...
Anabela Ribeiro, Jorge Silva
doaj   +2 more sources

Providing Multilingual Access to Health-Related Content

open access: yes, 2014
Finding health-related content is not an easy task. People have to know what to search for, which medical terms to use, and where to find accurate information. This task becomes even harder when people such as immigrants wish to find information in their country of residence and do not speak the national language very well.
Plumbaum, Till   +6 more
openaire   +4 more sources

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