Results 131 to 140 of about 678,986 (353)

Urban Transformations for Universal Accessibility: Socio-Educational Dialogue

open access: yesUrban Science
This paper offers a systematic review of the papers in the present century that have addressed the intersection between urbanism, universal accessibility, and the socio-educational sphere.
Susana Gómez-Redondo   +4 more
doaj   +1 more source

Population need and geographical access to general practitioners in rural New Zealand [PDF]

open access: yes, 2004
To use a geographical information system (GIS) approach to demonstrate the extent to which different areas in New Zealand vary in their geographical access to GPs, and to analyse the extent to which spatial access varies in relation to different ...
Barnett, A. Ross, Brabyn, Lars
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Transport networks’ accessibility and jobs’ accessibility: the significance of this correlation on the configuration of labor market and their consequences on social configuration in the city Bogotá [PDF]

open access: yes
Several researches have been done about transport in Bogotá (Colombia) but no one has treated the impact of the transport network on the configuration of employment in the city. This research has two different aims which are directly interrelated.
Carlos Augusto Olarte Bacares
core  

A new theory of space syntax [PDF]

open access: yes, 2004
Relations between different components of urban structure are often measured in aliteral manner, along streets for example, the usual representation being routesbetween junctions which form the nodes of an equivalent planar graph.
Batty, M
core  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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