Results 191 to 200 of about 4,064,536 (382)

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Identifying key complex relations between education and healthcare in the Netherlands for future pandemic management. [PDF]

Health Res Policy Syst
Hadjisotiriou S, Coenen J, Rouwette EAJA, Nespeca V, Oreel TH, Marchau VAWJ, Vasconcelos VV, Quax R, Wertheim HFL, Olde Rikkert MGM, Korzilius HPLM.   +10 more
europepmc   +1 more source

Catalogue of Free-Access Translation-Related Corpora

Tradumàtica: traducció i tecnologies de la informació i la comunicació, 2009
La utilización de corpus ha aportado nuevas perspectivas al campo de la traducción durante los últimos 10 años. Se han utilizado corpus en distintas áreas relacionadas con la traducción, como por ejemplo en los estudios sobre la traducción y, en concreto, la didáctica o la práctica de la traducción.
openaire   +3 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Unveiling alcohol bias and impaired inhibitory control in young binge drinkers: insights from the alcohol hayling task. [PDF]

Sci Rep
Carbia C, Almeida-Antunes N, Vasconcelos M, López-Caneda E.   +3 more
europepmc   +1 more source

Does Accessibility of Cannabis Mediate the Relation Between Method of Acquisition and Cannabis Use Frequency among Adolescents?

, 2022
Alexander J. Tyskiewicz, Patrice A. Arkfeld, Emma E. Smith, Jonathan Eilerman, Bradley T. Conner   +4 more
openalex   +2 more sources

A Scaling Relation Between Accessible Phase Space Volume and Escape Rates for Random Walks in High-Dimensional Hierarchical Energy Landscapes - Implications for Protein Dynamics [PDF]

, 2020
Andreas Volkhardt, Helmut Grubmueller
openalex   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Illuminating the path to more equitable access to urban parks. [PDF]

Sci Rep
Zhang K, Shang WL, De Vos J, Zhang Y, Cao M.   +4 more
europepmc   +1 more source

Evaluating the quality of life in Hong Kong's new towns in relation to accessibility and the distribution of community and cultural facilities: A case study of Tung Chung

, 2023
Inge Goudsmit, Darren Nel, Shuiyang Lin
openalex   +1 more source