Results 241 to 250 of about 708,845 (350)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Multimodal single cell analyses reveal gene networks of planarian stem cell differentiation. [PDF]

Nat Commun
Pérez-Posada A, García-Castro H, Emili E, Guixeras-Fontana A, Vanni V, Salamanca-Diaz D, Arias-Baldrich C, Frölich S, van Heeringen SJ, Cebrià F, Kenny N, Solana J.   +11 more
europepmc   +1 more source

How Does Immigration, in Relation to Gender Differences in Canada, Influence the Accessibility of Mental Health Services for Youth?

Hosseinzadeh Mohammad, Swaran P. Singh
openalex   +2 more sources

Accessibility, Usage Patterns of Forest Parks, and Their Relation to Residents' Behaviors based on the Theory of Planned Behavior - Evidence from Suqian, China [PDF]

Faziawati Abdul Aziz
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Imbalanced access to pediatric primary care in Switzerland: geographic differences and modeled future challenges. [PDF]

Eur J Pediatr
von Rhein M, Hauser J, Haldimann L, Jörg R, Gruebner O.   +4 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Down the Digital Delta: Health Information Inequities Among Rural Mississippi Caregivers. [PDF]

Healthcare (Basel)
Nadorff DK, Anreddy S, Sergi K, Ahonle ZJ, Stouffer C, Hemphill T, Buys DR.   +6 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Statewide Assessment of Public Park Accessibility and Usability and Playground Safety. [PDF]

Int J Environ Res Public Health
Obrusnikova I, Firkin CJ, Pennington R, Dixon I, Bilbrough C.   +4 more
europepmc   +1 more source